ID A0A1D1UHP2_RAMVA Unreviewed; 920 AA.
AC A0A1D1UHP2;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GAU88981.1};
GN Name=RvY_01585-1 {ECO:0000313|EMBL:GAU88981.1};
GN Synonyms=RvY_01585.1 {ECO:0000313|EMBL:GAU88981.1};
GN ORFNames=RvY_01585 {ECO:0000313|EMBL:GAU88981.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU88981.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAU88981.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU88981.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SMEK family.
CC {ECO:0000256|ARBA:ARBA00008809}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU88981.1}.
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DR EMBL; BDGG01000001; GAU88981.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1UHP2; -.
DR STRING; 947166.A0A1D1UHP2; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR006887; P4R3-like_central_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000697; WH1/EVH1_dom.
DR PANTHER; PTHR23318; ATP SYNTHASE GAMMA-RELATED; 1.
DR PANTHER; PTHR23318:SF0; SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3; 1.
DR Pfam; PF04802; PP4R3; 1.
DR Pfam; PF00568; WH1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000186922}.
FT DOMAIN 16..100
FT /note="WH1"
FT /evidence="ECO:0000259|Pfam:PF00568"
FT DOMAIN 185..376
FT /note="Serine/threonine-protein phosphatase 4 regulatory
FT subunit 3-like central"
FT /evidence="ECO:0000259|Pfam:PF04802"
FT REGION 113..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 662..920
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 665..679
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..701
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 702..718
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 729..746
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..872
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 877..892
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 920 AA; 104589 MW; 61B07331EBB4DFDB CRC64;
MTQSLTMDKS AENRRRVKLY VLNSARHWDD RGTGHVSALY SERLSGMSLI VRDEQSQQVL
LESKIDVETS YQKQQETLIV WSENESDMAL SFQEKAGCEE VWGKICQVQG KDPSVEVTQD
PLDDEDDEDS AGSLASYGPE PSSMTNASVP LPPCEIGKLD RIQEVVQAYM SHSHQREKLA
MAIEQEDYIR KLLECFKKCD DVENTDGLRQ LFSIMKNILM LNRNALYEIL FSDECLEDVL
GCLEWDPSGK APRKHREYVR DIARFKEVVP LENAELYQKI QTMYRVQYIQ DVILPSPSVF
EENILNTLQS YVFFNKLEIV NLLQDDERFL KALFAQLCAP ETSMEKRRDA VMFLKEFCQF
SHTLQPTSRE QFFRSLMAHG ILQGVQAALD VEDQRTRSAI VDVFTILVEM HPFVVREYCI
TQANKEPIDS NLFYVHVIRQ AVINDTDQQA SGAMQILTIT RLLLDPENML TSSNKNEKSE
FLNLFYRRCM PSVIEPILDI TKDDVLPAHE SIRRVQILNL ILEFLSYCVE HHTHHIRTFI
INRDLLKHVL VLLQSSHRFL VIGVVRFMRK IIGLPGQEAD FYHRYIVAND HLKPVIEVFL
KNGRTYNLLN SAILELFEYI RAEDMRQLIV YIVGKYWERL KDINYTTTFS LMKVRYEIHI
SPSPDSAARP STPDNSGEIR SGPRGSAKER RFRRDDRSMD EDEEHWFDET DENENGDTES
KEENGAPASE EEPTSSKYTP LTSVKSLAPI NAAPPVKRTL LDDLDEEDGQ FNGSTWKPGG
RINRKLPKKN SPVFKVSLNS APDSTREVST PPATSSNGPL FSNNSPSNNH TSVPSGRSWE
VTSTDTSKTP LPSLGKQSSL VSSTTFKSGA PSPSLVSYDD EDDEEEAEGE AEVSNGTEGQ
TAAVNGEVPA DRQQETVSTI
//
