ID A0A1D1UL49_RAMVA Unreviewed; 297 AA.
AC A0A1D1UL49;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 13-SEP-2023, entry version 14.
DE RecName: Full=Protein tweety homolog {ECO:0008006|Google:ProtNLM};
GN Name=RvY_00773 {ECO:0000313|EMBL:GAU87997.1};
GN Synonyms=RvY_00773.4 {ECO:0000313|EMBL:GAU87997.1};
GN ORFNames=RvY_00773-4 {ECO:0000313|EMBL:GAU87997.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU87997.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAU87997.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU87997.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the prominin family.
CC {ECO:0000256|ARBA:ARBA00006058}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU87997.1}.
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DR EMBL; BDGG01000001; GAU87997.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1UL49; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR008795; Prominin.
DR PANTHER; PTHR22730; PROMININ PROM PROTEIN; 1.
DR PANTHER; PTHR22730:SF1; PROMININ-LIKE PROTEIN; 1.
DR Pfam; PF05478; Prominin; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186922};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 196..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 297 AA; 32103 MW; EE24D8470A63DB1C CRC64;
MRSRKSVTQT TCFHNSGPYS FVAAKNLSGD INSSKSALDA LVNQIVILQS KTNDVSVAAK
NCGNAYGDCP PTSDARDQLA AMTSYMTSMV NTFTSLQTQM QTPIDQVNGA LNADYTGKAQ
AGLNTLINMS AIIMDKTTPL RSQIIAKLDD VPKQFEPVLS QIDGYLVPVQ EMFANQLAYM
RTFTPYINSY GKYGDIAVIV IATFVLLIAI MMLLGCATGA WSFDKAVPPT QRKGAVTCGN
FCLIFAVVLI LLFAWIFMIV TMVFFVGGTQ ADASICPVLQ GAPNNFTMLD DVRTSAI
//
