ID A0A1D1UUF7_RAMVA Unreviewed; 685 AA.
AC A0A1D1UUF7;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=[Histone H3]-dimethyl-L-lysine(36) demethylase {ECO:0008006|Google:ProtNLM};
GN Name=RvY_05270 {ECO:0000313|EMBL:GAU93306.1};
GN Synonyms=RvY_05270.1 {ECO:0000313|EMBL:GAU93306.1};
GN ORFNames=RvY_05270-1 {ECO:0000313|EMBL:GAU93306.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU93306.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAU93306.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU93306.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU93306.1}.
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DR EMBL; BDGG01000002; GAU93306.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1UUF7; -.
DR STRING; 947166.A0A1D1UUF7; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR Gene3D; 1.20.58.1360; -; 1.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR041070; JHD.
DR InterPro; IPR003347; JmjC_dom.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23123:SF37; JMJC DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR23123; PHD/F-BOX CONTAINING PROTEIN; 1.
DR Pfam; PF17811; JHD; 1.
DR Pfam; PF02373; JmjC; 1.
DR Pfam; PF00628; PHD; 1.
DR SMART; SM00558; JmjC; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51184; JMJC; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00022964};
KW Reference proteome {ECO:0000313|Proteomes:UP000186922};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 216..271
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 436..577
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
FT REGION 102..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 274..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..153
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 685 AA; 78386 MW; 38E62170B4F5E17D CRC64;
MDHHFCSDLG YTLHLMATFQ DVDCAAVWSS TEQSQIRNDP MALYPRTTSE SFGRIYDGTR
TNTLPAGRQE DTKYQVTAKL DPNKKLGRLK PPLADGAMGL KKLGKNKPDR EQQHFMNKSK
TFKVVTDNPA LKNAPILENK VEDRKRRSSE SVSSGNKKKS VAVDPKTPLT AEEALPNIKA
PVAEEERSQS PTPTSASERH KTGRRSAEKK PESNNSSTCI ASDCPKDPNL DEDFMIQCDE
CDEWFHGMCA FITEKQSNAY VWWFCTECIA KGQKPQKKPR TNNHRHDYYE PRPSKKPTQC
GTERFFEELS TKNLAPIVDV LIRKPGREID LDYMHNNGFT KPILIDDRAG LDLIIPERPF
TYDDVVKTIG ENTQVLAIDV TTQEDGVPLT LKSYLRYMMQ PPEEREVTLN IISLEFSKTE
LSKLVQPPRV VKELSWVDRF FENEDILPEA SYDRPDVQKY CLMSAKDSYT DFHIDFGGTS
VWYHIFKGKK TFFFIEPTPE NLALYKSWME DETHQSERFL GDETTCHRLD LVEGQTILMP
SGWIHAVFTP EDSLVFGGNF LHDLAVPNQL AIMDMEDQLQ TPDRYRFPHF YTVCWFALSE
MVGQLEDCFE QAKEPPAWLT QNIVPLYVRL KAWIEADGDL EKQKLRKAEI PDTLAEGKEI
LKKMDNFVKR LAKIKSVADA GKCTV
//
