ID A0A1D1UV14_RAMVA Unreviewed; 544 AA.
AC A0A1D1UV14;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 08-NOV-2023, entry version 20.
DE RecName: Full=Anaphase-promoting complex subunit 4-like WD40 domain-containing protein {ECO:0000259|Pfam:PF12894};
GN Name=RvY_02654-1 {ECO:0000313|EMBL:GAU90203.1};
GN Synonyms=RvY_02654.1 {ECO:0000313|EMBL:GAU90203.1};
GN ORFNames=RvY_02654 {ECO:0000313|EMBL:GAU90203.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU90203.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAU90203.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU90203.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- SIMILARITY: Belongs to the WD repeat CDC20/Fizzy family.
CC {ECO:0000256|ARBA:ARBA00006445}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU90203.1}.
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DR EMBL; BDGG01000001; GAU90203.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1UV14; -.
DR STRING; 947166.A0A1D1UV14; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0010997; F:anaphase-promoting complex binding; IEA:InterPro.
DR GO; GO:0097027; F:ubiquitin-protein transferase activator activity; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR033010; Cdc20/Fizzy.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19918; CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED; 1.
DR PANTHER; PTHR19918:SF1; FIZZY-RELATED PROTEIN HOMOLOG; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000186922};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 273..314
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 276..328
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 357..388
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 490..523
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 94..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 157..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 544 AA; 60311 MW; 2F2F639D038B2C13 CRC64;
MSGFAQQLVK KFRFLTDSGI GSSMDDNILT TGNDVVDGGN AENMRMDICR TPPSSPILAR
KKHYTSPVKS PDRYIPQREP RRWRIAYNCV GSEERTAKTT GTTTNRDDSK EGAEASQALY
QKLLRNEIMG ADMPEIMDEC ENQGHCGIIQ STSLNTSGLS ITSSPSSGQT KSSKRNVFTY
SPKKPSERLV SSSSPFSLSP LSEKSCQMLR QPRKVGRKIP KVPYKVLDAP ELVDDFYLNL
VDWSNLNVLA VGLGTSVYLW SANNSSVTRL CDLQLDSNAV TSVSWSERGH FVAVGTNKGP
IQIWDVQAQE RVTTLSYHAN RVGALAWNGD VLASGSRDRC IYLSDLREPP VYQRRKFKAH
NQEVCGLKWS PDHMYLASGG NDNKLFVWAH NASTECSPVQ TYTDHCAAVK GIAWSPHHHG
LLASGGGTAD RHIRFWNTLT GQALNSIDTG SQICNLAWSK HSQEIVSTQG YSQHQILLWK
YPTLTQIAKL GGHTNRVLFL ALSPDGESIV TGAGDETLRF WNIFSKCRSN KDRRSSLDIL
NAFR
//
