ID   A0A1D1UVR8_RAMVA        Unreviewed;       326 AA.
AC   A0A1D1UVR8;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   22-FEB-2023, entry version 15.
DE   RecName: Full=Lipoxygenase domain-containing protein {ECO:0000259|PROSITE:PS51393};
GN   Name=RvY_05650 {ECO:0000313|EMBL:GAU93759.1};
GN   Synonyms=RvY_05650.4 {ECO:0000313|EMBL:GAU93759.1};
GN   ORFNames=RvY_05650-4 {ECO:0000313|EMBL:GAU93759.1};
OS   Ramazzottius varieornatus (Water bear) (Tardigrade).
OC   Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC   Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX   NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU93759.1, ECO:0000313|Proteomes:UP000186922};
RN   [1] {ECO:0000313|EMBL:GAU93759.1, ECO:0000313|Proteomes:UP000186922}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU93759.1,
RC   ECO:0000313|Proteomes:UP000186922};
RX   PubMed=27649274; DOI=10.1038/ncomms12808;
RA   Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA   Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA   Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA   Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA   Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT   "Extremotolerant tardigrade genome and improved radiotolerance of human
RT   cultured cells by tardigrade-unique protein.";
RL   Nat. Commun. 7:12808-12808(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAU93759.1}.
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DR   EMBL; BDGG01000002; GAU93759.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D1UVR8; -.
DR   STRING; 947166.A0A1D1UVR8; -.
DR   Proteomes; UP000186922; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR   GO; GO:0034440; P:lipid oxidation; IEA:InterPro.
DR   InterPro; IPR000907; LipOase.
DR   InterPro; IPR013819; LipOase_C.
DR   InterPro; IPR036226; LipOase_C_sf.
DR   InterPro; IPR020834; LipOase_CS.
DR   PANTHER; PTHR11771; LIPOXYGENASE; 1.
DR   PANTHER; PTHR11771:SF180; LIPOXYGENASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00305; Lipoxygenase; 1.
DR   PRINTS; PR00087; LIPOXYGENASE.
DR   SUPFAM; SSF48484; Lipoxigenase; 1.
DR   PROSITE; PS00081; LIPOXYGENASE_2; 1.
DR   PROSITE; PS51393; LIPOXYGENASE_3; 1.
PE   4: Predicted;
KW   Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186922}.
FT   DOMAIN          1..326
FT                   /note="Lipoxygenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51393"
SQ   SEQUENCE   326 AA;  36443 MW;  33CAAB8A278225E0 CRC64;
     MWYNNADAAY HQSCTHLGFT HLMMEGIAVC THRNLSPSHP LFKLLAPHFL FLLAINTRGL
     QKLINPGGWV DKTTTMGCNG MFEIVKRGVK AWRLDVHAVP AVEIARRGVL DKTVLPYYPY
     RDDAVAVYEA IEKYVKSMVE HFYDSPEKVE EDGELQSWAA ELVKSKKRGG CGIRGVPGNG
     KFTDVEQIIV TMTAIISTCS LGHAAANFNQ YDEYGFPPNY PGILCGQVPT QKVGFTEKNI
     FDQLPSRSVT LDTMVVTRLL SSRGTQALGD FEVQYLYDPV SVSAAKQLRQ DLRSISEAIR
     KRNQSPHTKF PYPWLDPDGI PNSISI
//