ID   A0A1D1UW34_RAMVA        Unreviewed;       543 AA.
AC   A0A1D1UW34;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   08-NOV-2023, entry version 23.
DE   RecName: Full=mRNA-decapping enzyme C-terminal domain-containing protein {ECO:0000259|Pfam:PF16741};
GN   Name=RvY_04098-1 {ECO:0000313|EMBL:GAU91942.1};
GN   Synonyms=RvY_04098.1 {ECO:0000313|EMBL:GAU91942.1};
GN   ORFNames=RvY_04098 {ECO:0000313|EMBL:GAU91942.1};
OS   Ramazzottius varieornatus (Water bear) (Tardigrade).
OC   Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC   Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX   NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU91942.1, ECO:0000313|Proteomes:UP000186922};
RN   [1] {ECO:0000313|EMBL:GAU91942.1, ECO:0000313|Proteomes:UP000186922}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU91942.1,
RC   ECO:0000313|Proteomes:UP000186922};
RX   PubMed=27649274; DOI=10.1038/ncomms12808;
RA   Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA   Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA   Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA   Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA   Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT   "Extremotolerant tardigrade genome and improved radiotolerance of human
RT   cultured cells by tardigrade-unique protein.";
RL   Nat. Commun. 7:12808-12808(2016).
CC   -!- SIMILARITY: Belongs to the DCP1 family.
CC       {ECO:0000256|ARBA:ARBA00008778}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAU91942.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BDGG01000002; GAU91942.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D1UW34; -.
DR   STRING; 947166.A0A1D1UW34; -.
DR   Proteomes; UP000186922; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR   GO; GO:0008047; F:enzyme activator activity; IEA:InterPro.
DR   GO; GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
DR   Gene3D; 6.10.140.2030; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR010334; Dcp1.
DR   InterPro; IPR031953; mRNA_decap_C.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   PANTHER; PTHR16290:SF0; DECAPPING PROTEIN 1, ISOFORM A; 1.
DR   PANTHER; PTHR16290; TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1; 1.
DR   Pfam; PF06058; DCP1; 1.
DR   Pfam; PF16741; mRNA_decap_C; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
PE   3: Inferred from homology;
KW   Nonsense-mediated mRNA decay {ECO:0000256|ARBA:ARBA00023161};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186922}.
FT   DOMAIN          504..541
FT                   /note="mRNA-decapping enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16741"
FT   REGION          224..281
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          428..465
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        237..281
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        428..448
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   543 AA;  60086 MW;  37B3B4443BB02F7B CRC64;
     MSLSYVSRQV PRHQLFFKNQ AMSFKEEDPS AFSVNLIRKL DSSASEVISK ANDVKLYRYD
     TANEKWASTE MEGTLVFYRR LDDPSFGLIL LGRDPAHSHS WHQTFGSGVE LQSRSPFLLY
     RSFDALTGSL IEGLWFPSRE ECESMYNQIQ STTSQSSLPS YAAMVTGPVK KEEYSPEVKK
     KRNLLDGLEE NELKARTQAA EQAARVLHSK APACEHCGKT NHPSYRCFKK NGRPDQQQGK
     IFMNSNSGGS KPINIAKRDQ SNASSQYRSS QPQPSVLSPP NYTDAAILES KSTSSSSATA
     QMLSGVGYTR EEASAMTPIK LSSMMRHEAP QQPYLMPPIL NQPQPLMDMG FASNHLRGLL
     NLGSGQARQP ETPEHGHTNN LVNNSLSLSA SSVANMAEHG DGENVHRFVR DVSEKLGASA
     TGVVDSRYLG GSSTALSGES NDARRNSGQS GMALRPPHHF ESSMGGIQQD MGQQLLLPQH
     MDGMVANRRM ENGVGHGRDG VTVHPLTKDQ LLQAMEYLMR TDRDFVGKLH EAYIKSMMEH
     LRL
//