ID   A0A1D1UX48_RAMVA        Unreviewed;       254 AA.
AC   A0A1D1UX48;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=3'-5' exonuclease domain-containing protein {ECO:0000259|Pfam:PF01612};
GN   Name=RvY_05150 {ECO:0000313|EMBL:GAU93170.1};
GN   Synonyms=RvY_05150.2 {ECO:0000313|EMBL:GAU93170.1};
GN   ORFNames=RvY_05150-2 {ECO:0000313|EMBL:GAU93170.1};
OS   Ramazzottius varieornatus (Water bear) (Tardigrade).
OC   Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC   Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX   NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU93170.1, ECO:0000313|Proteomes:UP000186922};
RN   [1] {ECO:0000313|EMBL:GAU93170.1, ECO:0000313|Proteomes:UP000186922}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU93170.1,
RC   ECO:0000313|Proteomes:UP000186922};
RX   PubMed=27649274; DOI=10.1038/ncomms12808;
RA   Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA   Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA   Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA   Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA   Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT   "Extremotolerant tardigrade genome and improved radiotolerance of human
RT   cultured cells by tardigrade-unique protein.";
RL   Nat. Commun. 7:12808-12808(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAU93170.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BDGG01000002; GAU93170.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D1UX48; -.
DR   Proteomes; UP000186922; Unassembled WGS sequence.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR46628; PIRNA BIOGENESIS PROTEIN EXD1; 1.
DR   PANTHER; PTHR46628:SF1; PIRNA BIOGENESIS PROTEIN EXD1; 1.
DR   Pfam; PF01612; DNA_pol_A_exo1; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000186922}.
FT   DOMAIN          81..219
FT                   /note="3'-5' exonuclease"
FT                   /evidence="ECO:0000259|Pfam:PF01612"
SQ   SEQUENCE   254 AA;  28870 MW;  CBE71027344B66DB CRC64;
     MARVMDTNDG NGDFSMLKDN GKKKRVFLCN RMDEAELGQV YKVINRQSTI GLALTFDLKN
     LEAGLQNLTY IIVSTLDPSH MTYVFDCVSL DPIEILADLK TVLTNPHITK VVNDLYNSMY
     YLYHRHYLEV QDVMDIQISH RSLVQKREKG TESTQAQPSL DDMIRLYVDW KFAWPIKSKK
     KLNPVDLWSN PDPLCEVQIA DAALQGMYLL DIFQAQQQMI LANTVQRLGP EARGKLKDLS
     NKLADVSTSA KVPG
//