ID A0A1D1UY49_RAMVA Unreviewed; 456 AA.
AC A0A1D1UY49;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Receptor ligand binding region domain-containing protein {ECO:0000259|Pfam:PF01094};
GN Name=RvY_06318 {ECO:0000313|EMBL:GAU94574.1};
GN Synonyms=RvY_06318.1 {ECO:0000313|EMBL:GAU94574.1};
GN ORFNames=RvY_06318-1 {ECO:0000313|EMBL:GAU94574.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU94574.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAU94574.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU94574.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU94574.1}.
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DR EMBL; BDGG01000002; GAU94574.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1UY49; -.
DR STRING; 947166.A0A1D1UY49; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd06352; PBP1_NPR_GC-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR001170; ANPR/GUC.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR44755:SF11; ATRIAL NATRIURETIC PEPTIDE RECEPTOR 3 ISOFORM X1; 1.
DR PANTHER; PTHR44755; NATRIURETIC PEPTIDE RECEPTOR 3-RELATED; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR PRINTS; PR00255; NATPEPTIDER.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000186922};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..456
FT /note="Receptor ligand binding region domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008897750"
FT DOMAIN 122..428
FT /note="Receptor ligand binding region"
FT /evidence="ECO:0000259|Pfam:PF01094"
SQ SEQUENCE 456 AA; 51000 MW; 20C60664C904910C CRC64;
MRSVVVCLSF ICLLLKKCYP AESTMGSPSV YTSYGNVFPP LDPSSVPKLS AENSTVVTLC
ELWEDDGIPV TPGIDLALQR IGPHFALKNM TFRLLRHGIA GGCGDESVLA VGPALVDMHL
HQAPNGCQLL IGPSCSETMS NIRGLIEHWN IPVVTSGASG IKFADKQKTE VLTRFGYTQE
DVSLFLIRIL DHFNWTNVAF LYDVDTYATD FQSSFQQVLQ SSRLDIFKRI EFTKVMLGQN
SDKQWLKDTL VRSSERSRVF ILAALARNVY QIMVAASELG KLNSEYVYIT TNLIEAHRFS
DLFFFNNMAK SDPDGPRILG SLLVIRMKLP ADDLENKAEY DQFADAVKTN SLKYNFTYAP
GEQVTHLVLG VWDAVMFYGV ALNATLAAGG NIYDGRAITS RIWGHSFHGV VIECTISNYG
DRNFPYYLQD FSPKDAAFVV ERSQPKLHKI WSLYLF
//
