ID A0A1D1UZ05_RAMVA Unreviewed; 281 AA.
AC A0A1D1UZ05;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=ATP receptor {ECO:0000256|ARBA:ARBA00031974};
DE AltName: Full=Purinergic receptor {ECO:0000256|ARBA:ARBA00033052};
GN Name=RvY_06544-1 {ECO:0000313|EMBL:GAU94834.1};
GN Synonyms=RvY_06544.1 {ECO:0000313|EMBL:GAU94834.1};
GN ORFNames=RvY_06544 {ECO:0000313|EMBL:GAU94834.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU94834.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAU94834.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU94834.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the P2X receptor family.
CC {ECO:0000256|ARBA:ARBA00009848}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU94834.1}.
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DR EMBL; BDGG01000003; GAU94834.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1UZ05; -.
DR STRING; 947166.A0A1D1UZ05; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0098794; C:postsynapse; IEA:GOC.
DR GO; GO:0004931; F:extracellularly ATP-gated monoatomic cation channel activity; IEA:InterPro.
DR GO; GO:0001614; F:purinergic nucleotide receptor activity; IEA:InterPro.
DR GO; GO:0033198; P:response to ATP; IEA:InterPro.
DR Gene3D; 2.60.490.10; atp-gated p2x4 ion channel domain; 1.
DR InterPro; IPR027309; P2X_extracellular_dom_sf.
DR InterPro; IPR001429; P2X_purnocptor.
DR PANTHER; PTHR10125; P2X PURINOCEPTOR; 1.
DR PANTHER; PTHR10125:SF31; P2X RECEPTOR E; 1.
DR Pfam; PF00864; P2X_receptor; 1.
DR PRINTS; PR01307; P2XRECEPTOR.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000186922};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ SEQUENCE 281 AA; 33009 MW; 19A79F4518878BB8 CRC64;
MLRSHYNYTG QRYSVAITRE LYWRNILDRF SQEYLQNCRY HPENEPLCPI FRLEDIVHYT
NDSFERMAVK GGIIGFHIDW NCDLDYGVEA CLPRYFFRRL DSEDDKIAKG WNFRTAYYYY
DQNGTFHRDL AKYWGIRFVF LVAGKAGKFS TVHFILHVGS SLGLLGLASA MCEIFLSYHR
SRRVNDLKFE YLAKKKPMKA QRRYSNMSAP QLQWDVINQN GHGTYAPDHR LQVRSASASP
NRIRHTSVTP VLDRRIVRRS YGSKKSMFSL GNRNGGNPVW I
//
