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Database: UniProt
Entry: A0A1D1V0T1_RAMVA
LinkDB: A0A1D1V0T1_RAMVA
Original site: A0A1D1V0T1_RAMVA 
ID   A0A1D1V0T1_RAMVA        Unreviewed;      2692 AA.
AC   A0A1D1V0T1;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   07-NOV-2018, entry version 13.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GAU93572.1};
GN   Name=RvY_05495-1 {ECO:0000313|EMBL:GAU93572.1};
GN   Synonyms=RvY_05495.1 {ECO:0000313|EMBL:GAU93572.1};
GN   ORFNames=RvY_05495 {ECO:0000313|EMBL:GAU93572.1};
OS   Ramazzottius varieornatus (Water bear) (Tardigrade).
OC   Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC   Ramazzottiidae; Ramazzottius.
OX   NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU93572.1, ECO:0000313|Proteomes:UP000186922};
RN   [1] {ECO:0000313|EMBL:GAU93572.1, ECO:0000313|Proteomes:UP000186922}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU93572.1,
RC   ECO:0000313|Proteomes:UP000186922};
RX   PubMed=27649274; DOI=10.1038/ncomms12808;
RA   Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA   Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA   Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA   Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA   Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT   "Extremotolerant tardigrade genome and improved radiotolerance of
RT   human cultured cells by tardigrade-unique protein.";
RL   Nat. Commun. 7:12808-12808(2016).
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:GAU93572.1}.
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DR   EMBL; BDGG01000002; GAU93572.1; -; Genomic_DNA.
DR   Proteomes; UP000186922; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 4.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000186922};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186922};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2234   2254       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2266   2284       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2312   2330       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2350   2378       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2399   2421       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2507   2530       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      130    184       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      191    243       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      252    308       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      315    381       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      387    454       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED      518    538       {ECO:0000256|SAM:Coils}.
FT   COILED     2645   2672       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2692 AA;  305875 MW;  452034CE78FD25BD CRC64;
     MIRKMLGLNE DTSVSFLRMG DIVSLYAEGI SNDASPDSGF LSSLGLVDER CIVQPDAGTL
     DVPPRKFRDC LFKICPMSRY TAQNQFRKSK LARQQTNSFT LTPSSLMSKL HHAAEIEKKQ
     NDNESKKLMG TPILYGAIVQ FLHLKSNKFL TVNKHLPAMV EKNAMRVHLD SAGNEGSWFY
     ISPFYRLRAK GDTVVAGDQV IIIPVNAAQP LHVSSMSLSD YPGCREVNAI QSLEPCPWKL
     SVYMDYKDAS SEHILKSGDV IRLFHSEEEK FLTLDDYQKK QYVFLRVTAR GSAATATSSK
     ALWEVEIVKN DPCRGGRATW DSLFRFKHLA TGAFLSAQVD NDTTSDVVRN KLRGGPGTPV
     YYLTPHTQDF DRTCLFELHP TTSVKRGSSI PKKQTFARFK HYDTNSWIHS TTISFDKTPP
     AGTKTGSEPW RPVMDKVGLA VQRDDKEAFA IVPVAADEVR DLDFANDTAK SLAGINSKIA
     DRTATRSDIS ILRKVLTDTI YFVADTPDKG GDCLEMVAET LNREKQKLMR EQNVLKQVFA
     ILRTPFADET VLEKKPYFYL EDLNDPRQAH LKQVMRYCYR LLRLAQQDYR KNQEYVAKEF
     SLMQRQIGYD ILAEDTITAL LHGNRKLLEK HITEKEINTF IKLAQRNKDS KFLDYLAQLC
     VSNQTAIPAT QLLICVAAFN SNNSDILIRT RFERDDDDFS GYNNSPVFLD WNHQTQSLSE
     LTRLARNVAN PEVTKWLDYY RHQLDLFSHM CLDRQYLAIK ELAPELTVPL TLRCLADDNL
     QPELRASFCR LILHLHVDKG DQKLITPVRY ARLWNDIPSD CTLEGFSHMA EKSISAEEGF
     ESLVSFVHRY LEKCSEHAGL SKVGDQNQTF ANREQNKLTF EVVKLTRYLV YFGFFSFSQL
     IHLTRILLAI LDVDTTEGQI PTDSEGSGDE ADESRSFARI RTALSSPVSL LSNLTTGLAN
     DYGRQTSVLT EQEEKLVVDT KVKIIEILTF VLDIRLDFKI TRLLSVFKQA AQGYGQSPSS
     SKSRTASDQC ELSASPSRTV HKEFDALFQD KELNLDGEEG RLFIRVLLHL AMHDDPQLVT
     GALKLLFRQF SQREELLQAF SQVQLLVSPA QEEVYIKIKN DLDAFRGYVE KSELWVYRST
     KEGATEKEND TVAPPQPLAP RNSLVRNPSL VSFSSVARDS LTSELPDMGS PMLDEYDEIQ
     KIFCSVNSLC VYKDKKTGSR KPRFQEQRLL RNLGFHTIVI HLLQIPYEKN LDHKMQKIIA
     DAHEFLQNFC LGNPDNQRIL HQDLDLFLTP SPVECMTVRS IFEGNYDLCS EVTPHVVQHF
     ISCIENQGEN VEYIRALQAL VYADNRFVKK TQDLIVSELL SSADSEVLLF IADRNGFENL
     LCLMESVVDD DKVPGDLRYH VELIRLLSMC TGGRNHFTEL KCHNLMPLED IIRLIAHKSC
     LIMVKCVYVD FLTNCFVETE MENKEIFSSS STGIWTLFED FAKDIDEACK TEFQPSRQWS
     LHYYVATAVV KLLTDFFKTA FPTSTGRPKL QDSDQVQLME RLLQSLIRLC GQNWVKTDKS
     FQANVSSCLK ELKEAATRVG SMPSHLGVQV ETALERGKLR QPLPVSSKLS NCAKSVEAIS
     GSLQENLSRD DQEILNSLQE IVTKIQLHGN NLALAEKSLI VDVVQYPEIL FSSRSKTRPR
     YQGGELIRKL ITHVSVLQES DELLCLQILH VLRSMIIEEV KDEQKFSKEG ANLRRDFLAA
     CLDRRMRSRW QRPEGRSKDL IISEIQCHLN AKGASALVVD LIVKKTSPEV LRASVVLGIA
     LLDGGNTAVQ KSLFDRLKSG EDSEKFFAVF DTKMKAAQSR LRSSQKIVWS EADDADMLSE
     SSQRDRIQNS VSDGNLAVRS PSRRPSTSSL RSTSSTPQPR WSVTIDNDDA ETVKDEPLSP
     EVEIMTNILR FFQLLCENHN RDMQNYLRVQ GGRTSCNIVL QTLSFLDCIC GSTSGGLGLL
     GHYINQSNVD LVNQTIVTLT EFCQGPSVEN QDCIAGTETD GLDIILAIML TDIRPLQDKA
     EDKVLLLKYN TVKLLLAITE SRRDTDNAEK ILRNLSLGSF VDSIVHYHYL SDGTKKTGTE
     DAPTPRMLAG SMYILAYQLA EFSPDLWHLL HPSDFDSTPK MVDALKYLDS KTAHIEVVRE
     DRSIEKITFR IAEKCEYLTP ETKQRVKNET ERDEQGSKVA DFFGRVDELY NEMKWQKHLR
     ETPMLYQISQ RMTLWRSLNV FFAWLLNIMV MMYYPFSGSI SDIPFVYSNF LWIMFFFALA
     MVIVRPEKSY FKPLVITAIV RSVYLVGPQY TVMLLGVINV IVSAVTVVSY TGNIGAAESS
     ISGALKDSRF FYAVTLVAIS VAGLVVHEFF YSLLLLDIVY REETLYNVVR SVTRNGRSIL
     LTAVLAVILI YMFSMVGYLF FSHHFIKEVS TVTSLLLPEK TVVGSNEASK IIDLNQETEM
     EHVCHSMLTC MVTTLLHGLR SGGGIGDVLR QLSFKDPLFF ARAVYDLLFY FVVIIITLNL
     IFGVIIDTFA DLREEKQEKE EILRNSCFIC GLERSAFDNK SISFDQHIHS DHNMWHYLYF
     IILLREKDPT EFTGPESYVS SLIAENQLHW FPRLRTLSLA VEDKDSDQGE IQKIQKELLI
     TQQIVIKLSE QLADLRREIK EQRSRRDRMK SMPAGHIFNQ SINGYDDAFD PF
//
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