ID A0A1D1V8B6_RAMVA Unreviewed; 257 AA.
AC A0A1D1V8B6;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Exonuclease domain-containing protein {ECO:0000259|SMART:SM00479};
GN Name=RvY_08502-1 {ECO:0000313|EMBL:GAU97150.1};
GN Synonyms=RvY_08502.1 {ECO:0000313|EMBL:GAU97150.1};
GN ORFNames=RvY_08502 {ECO:0000313|EMBL:GAU97150.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU97150.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAU97150.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU97150.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU97150.1}.
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DR EMBL; BDGG01000004; GAU97150.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1V8B6; -.
DR STRING; 947166.A0A1D1V8B6; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0000175; F:3'-5'-RNA exonuclease activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd06133; ERI-1_3'hExo_like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR047201; ERI-1_3'hExo-like.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR23044; 3'-5' EXONUCLEASE ERI1-RELATED; 1.
DR PANTHER; PTHR23044:SF61; ERI1 EXORIBONUCLEASE 3; 1.
DR Pfam; PF00929; RNase_T; 1.
DR SMART; SM00479; EXOIII; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000186922}.
FT DOMAIN 3..209
FT /note="Exonuclease"
FT /evidence="ECO:0000259|SMART:SM00479"
SQ SEQUENCE 257 AA; 29986 MW; C8B1D86C7CBBF51A CRC64;
MDYVVVIDFE ATCDVGQRIG QHVNQIIEFG AALVNVQTQQ IESTFHKYCQ PSGTLRILSQ
YCMNLTGVIQ ANVDSAPQFP EVLRSFEEWL LEHRLSPNPD SSVSYMSRRT VTFRWILASD
SMYDYTIYLY NECKLNNIPY PSYAHRILTI GSLFKNNYLH VPARTRMPNG LARMLEHMDM
EFEGRRHSAL DDAWNLARIV VRMVQEGHRY SLRATIEVLP DHQQYSNHSM PNSCGYVDLL
EREMEDALDR MFSHRFF
//
