ID A0A1D1V9M4_RAMVA Unreviewed; 809 AA.
AC A0A1D1V9M4;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Polymerase nucleotidyl transferase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=RvY_07842-1 {ECO:0000313|EMBL:GAU96387.1};
GN Synonyms=RvY_07842.1 {ECO:0000313|EMBL:GAU96387.1};
GN ORFNames=RvY_07842 {ECO:0000313|EMBL:GAU96387.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU96387.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAU96387.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU96387.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU96387.1}.
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DR EMBL; BDGG01000003; GAU96387.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1V9M4; -.
DR STRING; 947166.A0A1D1V9M4; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:1990817; F:poly(A) RNA polymerase activity; IEA:InterPro.
DR GO; GO:0016070; P:RNA metabolic process; IEA:UniProt.
DR CDD; cd05402; NT_PAP_TUTase; 1.
DR Gene3D; 1.10.1410.10; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002058; PAP_assoc.
DR InterPro; IPR002934; Polymerase_NTP_transf_dom.
DR InterPro; IPR045862; Trf4-like.
DR PANTHER; PTHR23092:SF15; INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED; 1.
DR PANTHER; PTHR23092; POLY(A) RNA POLYMERASE; 1.
DR Pfam; PF01909; NTP_transf_2; 1.
DR Pfam; PF03828; PAP_assoc; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81631; PAP/OAS1 substrate-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186922}.
FT DOMAIN 211..303
FT /note="Polymerase nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF01909"
FT DOMAIN 375..434
FT /note="PAP-associated"
FT /evidence="ECO:0000259|Pfam:PF03828"
FT REGION 132..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 688..809
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 506..520
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..565
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..637
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 689..777
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 780..794
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 809 AA; 88158 MW; FBB2B5EE79032E94 CRC64;
MALSACAKEV WLQPEQLGRT SRDWSDITRG ANKSSSAAAN HLANLSSHFL PCLSSNGYNA
NMTRQAAQQL DSRFSPAALA NLPPQLLPLA LHGIAAAAAA AAAQQNTHQS TSSLQRNASS
NPLASHLPRS VLQHHPSSAP QLRPRDNRPI VASSAPNSLT KMYGGTPWIK DKPYKSGIDR
LHEEIEDFYE YMSPTPAEKR MRKDLVDRIG NVIKGKFPNV EVDYFGSFRT SLFLPTSDID
MVLFGEWQGP PPLFALKDML IQAGICTPDG VKVLDKASVP IIKLTDKRTR VKVDISFSSS
VVKNNGIRSA ELINGYMTEY NCLAKLVLVL KQFLLQRDLN EVFTGGISSY SLILMTVSFL
QLHPRYQPKA EVPKLGVLLI VFFELYGKHF NYKDTAIRVK DGGSYIPKEE MERSMPDGLT
ASVLCIEDPL QPGNDIGRSS YGALQVKHAF EYAYSQLSHA VFDDGGFVDV DADGDSASPS
ILGRIIRITD DVIDYRRKVE KEFGTAKDGK ETKKQEKRSY ANILRSPPKQ QPELLMSCGS
SAVSSSSFDN RSVTSGESGA SSMADSDTEL EGPVGSCSTL REETSMKKGS LSSVGKSHER
PGSAPPAGLG RNGVSTRDAS VQSEDRTSKE DEDGNASDTN SIRSARSQPE VIKIVSYNDP
TAQTLSTRSL DGGESSYRIA VLGNFPRGPS GVRSSQSLHN HSQPNLPLHS PIVVSGNGPS
FRTSGFHAQQ AQPQRRPPQY NGNGWEGSNG DSEENWHQGS SRVYRQGQQQ GGMRGSENFG
GNRQRKRGDG PPTSVRRGDG KGNSWNYKS
//
