ID A0A1D1VA44_RAMVA Unreviewed; 582 AA.
AC A0A1D1VA44;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 03-MAY-2023, entry version 23.
DE RecName: Full=ETS domain-containing protein {ECO:0000259|PROSITE:PS50061};
GN Name=RvY_09643-1 {ECO:0000313|EMBL:GAU98506.1};
GN Synonyms=RvY_09643.1 {ECO:0000313|EMBL:GAU98506.1};
GN ORFNames=RvY_09643 {ECO:0000313|EMBL:GAU98506.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU98506.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAU98506.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU98506.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU98506.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BDGG01000004; GAU98506.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1VA44; -.
DR STRING; 947166.A0A1D1VA44; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF190; ETS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000186922}.
FT DOMAIN 488..571
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 43..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 142..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 450..485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 582 AA; 64429 MW; B2BEDDB5623CDF7D CRC64;
MMLRSAGLRR TLPVMANSDR SLQCYGSLGS RQCSVRKAPV VVGSPPSFSS AQSNHRVLPA
DPSSARSSSS FHKQAGPALD RFPVYNHPAS SVTNARMYPP ETAVAPPTTG GSPAASSQIQ
EVFHTQHRSA YQNNVQNQSM QSFDHTSLHP GSNKNHNGTP NVSFTHSSSY PVITRTSGNF
DSSQYNGGHG QPLPPLAHFN EYIAKTQMTA ALNRNPYGIA ASEGHGAELP TKRICAWNPA
DVASFFRAVA RDNGQDPSRL NVGKLYGLDG PALLRLDEID FLERDPMNGA QWYRALRKFV
DRPQVGMFTP KMEPGETSPY VTDPHAPFLT SQQSSGPFHD DYSEYIQESF TKDEFDDIDI
ADSSVVYGNG PQQLHYAPSH TSQTFNGNTV VFQNFSPMSL CGTSMTSDGT ETVKTDLDSD
MESSRSCTRS SYTDNMSGQS LSSYNFESVS PRWSSSSPES SSSKRQFKPS PKSEKLKKSS
SKHGTRGNHL WEFVVKLLKN PVQDGKQIIK WENKAEGVFR FVESEKVAKL WGQQKANPRM
TYEKLSRAMR YYYKSRILLP VIGRRLVYQF GPKASGWRSS TC
//
