ID A0A1D1VCH0_RAMVA Unreviewed; 408 AA.
AC A0A1D1VCH0;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=protein-histidine N-methyltransferase {ECO:0000256|ARBA:ARBA00012533};
DE EC=2.1.1.85 {ECO:0000256|ARBA:ARBA00012533};
GN Name=RvY_10356 {ECO:0000313|EMBL:GAU99336.1};
GN Synonyms=RvY_10356.1 {ECO:0000313|EMBL:GAU99336.1};
GN ORFNames=RvY_10356-1 {ECO:0000313|EMBL:GAU99336.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU99336.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAU99336.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU99336.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. METTL18
CC family. {ECO:0000256|ARBA:ARBA00038126}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU99336.1}.
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DR EMBL; BDGG01000005; GAU99336.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1VCH0; -.
DR STRING; 947166.A0A1D1VCH0; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR019410; Methyltransf_16.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR14614; HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN; 1.
DR PANTHER; PTHR14614:SF39; HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG; 1.
DR Pfam; PF10294; Methyltransf_16; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000186922}.
FT REGION 66..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 408 AA; 45565 MW; F750F8F13477CDD9 CRC64;
MFGKSWYGRL AVRWQQFLII VAASRAAGLR LRHMIAPRSN MAFMFNFSFP ELSDLTEGNV
FHGAAPSTAA AAQPEEERKA SESTTGSRSD VYDLTQSGTV EDKKLLPFKE HRVFRQTDET
TASDEVKLDT ALLLSATVIP ETEWNTLAVG DITLQFVSPE WLDRKLYNLP EAEVTSEGAT
ASDIVPNVYE GGFRVWDGAC DMLSFLVTSD HVILKDKKVL ELGCGAGLPG IFALLQGADV
YFHDYNAEVI QSATIPNLQQ NVLVANKTVR SEVASRTHFF SGDWLSFAEQ LNSTKGDHMN
EDVSREDKAM YDVILTSDTV YRKDVLQKLC FVLPLLLRKE GTIYLAGKSH YFGLDGGTDE
LRMELSKQNK LEVIASKEYP DCVRREVLTI RWKPKTNDSA SSTRSFNS
//
