ID A0A1D1VG43_RAMVA Unreviewed; 284 AA.
AC A0A1D1VG43;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=DNA ligase 4 {ECO:0000313|EMBL:GAU99032.1};
GN Name=RvY_10091 {ECO:0000313|EMBL:GAU99032.1};
GN Synonyms=RvY_10091.2 {ECO:0000313|EMBL:GAU99032.1};
GN ORFNames=RvY_10091-2 {ECO:0000313|EMBL:GAU99032.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU99032.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAU99032.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU99032.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU99032.1}.
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DR EMBL; BDGG01000005; GAU99032.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1VG43; -.
DR STRING; 947166.A0A1D1VG43; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:InterPro.
DR GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR029710; LIG4.
DR PANTHER; PTHR45997; DNA LIGASE 4; 1.
DR PANTHER; PTHR45997:SF1; DNA LIGASE 4; 1.
DR Pfam; PF04675; DNA_ligase_A_N; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:GAU99032.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000186922}.
FT DOMAIN 61..261
FT /note="DNA ligase ATP-dependent N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04675"
SQ SEQUENCE 284 AA; 32653 MW; B9F02AB2FE8C54B0 CRC64;
MDVLREWFVS AFQVSSMSIC FCSRLPVFVR RTRTPSSVRL SGFHSLWIIA GRMAVERSAK
YTRFVALCEG ISKLGTSKDR KRNLLHNFVE GWRMSYQQAY PSNPQPASEM FFPFLRLLLP
EADRDRPAYG MKETVLARMF IQELSLVKGG KASETLLHWT KNKPQGADHR EVADFAGVAY
HVLQDRLSKD GYETGMSIYD INKFLDELGE ANGVGGENRK ERTNRAFREM LRQLERLEWK
WLIRIILKDA RLNMGKECIL TVCYPDAAEL YDATTSLSGV LNLY
//
