ID A0A1D1VJK4_RAMVA Unreviewed; 2781 AA.
AC A0A1D1VJK4;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
GN Name=RvY_09792-1 {ECO:0000313|EMBL:GAU98678.1};
GN Synonyms=RvY_09792.1 {ECO:0000313|EMBL:GAU98678.1};
GN ORFNames=RvY_09792 {ECO:0000313|EMBL:GAU98678.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU98678.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAU98678.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU98678.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU98678.1}.
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DR EMBL; BDGG01000004; GAU98678.1; -; Genomic_DNA.
DR STRING; 947166.A0A1D1VJK4; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 18.
DR Gene3D; 2.60.40.60; Cadherins; 19.
DR InterPro; IPR039808; Cadherin.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR PANTHER; PTHR24027; CADHERIN-23; 1.
DR PANTHER; PTHR24027:SF445; CADHERIN-87A; 1.
DR Pfam; PF00028; Cadherin; 10.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 16.
DR SUPFAM; SSF49313; Cadherin-like; 18.
DR PROSITE; PS00232; CADHERIN_1; 3.
DR PROSITE; PS50268; CADHERIN_2; 15.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000186922};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 261..359
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 373..470
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 628..705
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1218..1324
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1518..1616
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1715..1815
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1831..1919
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1919..2018
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2019..2123
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2140..2235
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2249..2337
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2373..2478
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2497..2578
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2579..2682
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2683..2780
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 2781 AA; 298290 MW; 0C2500E0B8F64829 CRC64;
MDILRPSGRG KMKRRRSFWI LFRFFLLLKI VVPIMSRTEL HVQNTTILSI FGLEYSTTTS
PSFTETTKQE VLAADGSRTA KPEFLTWNLT LDSLQALDKS NKTGIQPDLS EADVRSFLHE
MDPRDDQPLG TTTESPRHFD SLIPDRSFIP IPIVRLPAHV LATPRTPPIA HFPISGTPVT
PAIPRPAWHE MENDASASEY LPIYPSTSSN WAAREPEFFI SHAGADASVH YSRVQVAPTG
NPEQPWFRLP SPALSSSSVI NPSSFRAQVR EDAPIGTPVS IVRRNDVRGP LSPYSIVRGD
ERRQFQIDPS GRIAVAAPLD REMMGAYNLT IRTVDHTGNE VLSSVYVEVV DVNDNAPKVG
YQDTRFTVPC NVPNAIIGTI HATDDDVGRN GQVYFYLDQD HSTPGRFYID PISGTLATSM
ALPAEPDHYT MHVTARDQGM EVQLQTTLEI TVDVLCNAPV PSRQYGPPVP QTTARSNNVS
PQFTAPFYEF IVSICDQRAI PVGSVAAKDP NVGLLGQLIY TVNDRNVAVN PTTGLITLNT
PVSRWQAPMR FPVMVTDGGG LSAVVNVTIS IRCQAALPAV LPGYGAAPST ILAPTLPYPN
RPPFFVNGSL VFDVECVGPI DIIGYAVARD ADEGVYGEIN YSLSGPDASL FWIAQNGALR
TSSALTLPRY LITAVARDGG NAFSQTLVTV NNNCEQALRC LPPNYSFEAD ERIPPGTIIG
RISARGRNLA YRIVTNGADQ VFAVQPQTGI ISSRQTMAAL QSSPAPSASR TANFVVRATQ
PASERRRETF CDISVFVTVN FTLSSAVPPA ALEFANQSYH FIVGCVGPST LIGIFQAQSN
HPRAFFDISG PQAAMFEVSP TTGEIRARYQ LVEGGTQVYS FLAGLSTPGS GFTRRQVPVT
VEVSCRPFNC PTSVTIQVAE DAVVGSVIGQ IPSTISTTQD SPGSLFYRLV APITSPLSVV
VDPKTGEITL GQPIPALGTS AASSQFEFVV AVFDARGEGC KISVNLAITR HKRPPEFVGS
PYVFTAVCGR LGGVVGRVTA VWLTGGFQPA KVTYAISGGN EQRNFMMDGV SGELRVAENV
PEGRYVLQIR AHDGNGLLST TTATVNVPKC PLDCPDVLRA QINDNAPPGT GIAFIPDPTA
GSSSGSVTYR ISPMAPEDVR NVLAVDPFSG SVVLNERVSE HGGEMMRVPV IVQSTSDQTC
EIVLEVGIVR RLPSLPSCPS PSSVSLLQSS RVGTVVTDWK LSPEPGEYTY SLVATSGAGD
YFDIDKSTGT IVVTHDLFSL PARTYQLILR GSMLNDVTVF CDGRVDVTVL PVNLTLQCAL
TPLIATVDRN LELYGPDRTI AIVRVGSPNG YPLRFSVLSN EVSGVPLISV GRSNGIVSLT
RGVSLASMVE YQYVVRAMDP YGAYCDTTLI LKLPPVNRRP VFASEQYVFS STCGPADTFI
GVVPANDPDG DQLTYAVTPS EFFTIDSLGA IRSRVPVLTV IPSQGLTVTA SDPAGHKTTT
HVKVAFDGVG CGSPPVCSQP VYRFELPSNA PQGTRVGTVT ATDLDGDRLT YTLFGPDQSA
FTVNPTSGEI QTARSLSPLP SGQTAFQFAV RASSAANAFC QMTVQVTVPP SSAPQFAQPT
YEFNVPCGTP IRCLGRVNAV EGNGGGPVQY SMSSTDRIFT VTPDSGEVCL RENAMPLPLR
RQSAVVSARN PMSGATTTAG ISVTLQPCQR APVCSPPVLT SAINEVDPIG TKVQQVSATD
PDGQDALSFD IVDGNREEAF TIDHLSGVIV TNRPLDRERT RSYRLTVVAK DTSEATCQVV
VDVAIIDNND NAPVFEKTVY EFRAKCREAL TYVGTVSAVD DDIGMNAKLV YSVAPSSPVV
IDPETGEIRT RLPLDNNQGD VYEVVVFASD AGSPQKTASV DVRITTNCSE AQTNLAPICP
LPTSLRVREK SPPNTLVTQV AALDPANRPL RYQLGGPYAS RFSVTPSGQV LTRNVVERET
MVSPFSLSIQ AFNKEGLSCT TMLTITVLGG STDEQPLAFV GPRSFAVDCA APGGTVVGQV
SATGNVQTSH VEYSLSGTTD FIIDKVTGQI RILRPLSAQL PTREIVVLAN DLASPRRSAQ
VTVQVTIRPN CPGVVVTYSP PQFLQPGYSF SINCGHMGLI GVVSTQDGDG ETSQPGSMLY
TIADATDGAR EVFLIDATSG ELRARRPVSG SPASYQLTVL AADNSQVPPR SATVKVQIVV
RCLPTSTALY LPPTCPQSSV ANVPEHRSGL LVATVVARNP NPDSSLKFSL RPSADSQPFQ
IDNINANSAR IALISPLERQ RQSTYIVDIN VVNIYGQSCE TSIRVNVMDA ANPLPSVQPL
ANDDGSSERK ALLVPQSPTL HCLGLRAPGL TDQRAVLEIE LEEHMPVGTL IGIFETATVP
TIASQPLGQV AYRISSGNSD GAFLLDSSTG ELKLAGEIDR ETRDFYNLTI SATDRSASVC
SAAVFVRIDD VNDHAPEVVN MQPVVANVNC STPNAFIVQL SVVDRDLGRN GEVSFFLENN
SGFQVSSTGE VRTTMGLSRD PPARFVAVRI SDHGTPTLSS TVTLTINVAC PPASIPTFQQ
QYYCAGIPEN SPLNTEITRV KALYPDNRTD VSYVLRSGNS NLFSVEAKTG IVRSRAVLDA
DAVASEDYSL VIGTLQNDQT TPDAYAVVFI NVLDVNDENP RFESLEYRRT IPSTVLLDSG
LLSVRATDRD QTYPNNHIRG YELGGNVAMV QQYFRIDSAG ELVLSQPLTA FRGQTITITV
IAVDGGNPPR TGTTTIFLAV I
//
