ID A0A1D1VL02_RAMVA Unreviewed; 609 AA.
AC A0A1D1VL02;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=F-box domain-containing protein {ECO:0000259|Pfam:PF12937};
GN Name=RvY_12289-1 {ECO:0000313|EMBL:GAV01601.1};
GN Synonyms=RvY_12289.1 {ECO:0000313|EMBL:GAV01601.1};
GN ORFNames=RvY_12289 {ECO:0000313|EMBL:GAV01601.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAV01601.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAV01601.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAV01601.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAV01601.1}.
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DR EMBL; BDGG01000007; GAV01601.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1VL02; -.
DR STRING; 947166.A0A1D1VL02; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0080008; C:Cul4-RING E3 ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0019005; C:SCF ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR042508; FBXW5.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR20995; F-BOX/WD REPEAT-CONTAINING PROTEIN 5; 1.
DR PANTHER; PTHR20995:SF17; F-BOX_WD REPEAT-CONTAINING PROTEIN 5; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186922};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 91..130
FT /note="F-box"
FT /evidence="ECO:0000259|Pfam:PF12937"
FT REPEAT 172..205
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 526..558
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..55
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 609 AA; 69686 MW; B6667FBE67EF5393 CRC64;
MSSLSRHHAS QFGLPSRRRR TSTIVDEGCS PDREILARTP TMDDPDGNFI DDGHRRDFSV
QYGGEEASTS QEKRNSTSDS SIDGWSELYL DIMVRVLSEL SVQDIASCAR ICQNWYKSTQ
HDLVWKNIFA RDFKIDTRAR RKNIQDDERF STWKSEYKRL TYEVPLIQVQ LIRDHRDEVL
HVSFSHDGRM FSTCSKDGFV KCWDVTEFPY RRKFQSNMKS NFAWKYTQYS VFNSSDTLLL
VSGVHFGPLS TSGELVVFST QDDFSVQCKV RNKPYDIFGS WLNDDHLFSG NLHWVTGVDS
CCSLWISKAS QELESERVAV MRRAYKFLNV NGSSLRTLLV ACPKDGPEDE TLMIFSTGSQ
TYIPHQIGIK KLKKATIPFP GTTVHRTLRE AMDEHDREME NAEAGQPPPI QYDTVDHVFE
LSAQIIGLCL SPDQRYLFAN CRSWPQDVRI TDPFVPPPIS SQIEIRCYDL LTLKEAPHIY
RAHRAFTPSE ECFFIFVDVS EDFVASGAED SKGYIWDRHH NITLSSLQHQ SVVNSVAFCP
ADQETLVTVS DDYTIRVWFS RRKCQEMGMK YQGQKICGVD KSVQCAVDKA DTELAGTVGE
SFHPCSDYP
//
