ID   A0A1D1VMM4_RAMVA        Unreviewed;      1435 AA.
AC   A0A1D1VMM4;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=DUF4456 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   Name=RvY_10702-1 {ECO:0000313|EMBL:GAU99748.1};
GN   Synonyms=RvY_10702.1 {ECO:0000313|EMBL:GAU99748.1};
GN   ORFNames=RvY_10702 {ECO:0000313|EMBL:GAU99748.1};
OS   Ramazzottius varieornatus (Water bear) (Tardigrade).
OC   Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC   Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX   NCBI_TaxID=947166 {ECO:0000313|EMBL:GAU99748.1, ECO:0000313|Proteomes:UP000186922};
RN   [1] {ECO:0000313|EMBL:GAU99748.1, ECO:0000313|Proteomes:UP000186922}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAU99748.1,
RC   ECO:0000313|Proteomes:UP000186922};
RX   PubMed=27649274; DOI=10.1038/ncomms12808;
RA   Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA   Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA   Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA   Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA   Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT   "Extremotolerant tardigrade genome and improved radiotolerance of human
RT   cultured cells by tardigrade-unique protein.";
RL   Nat. Commun. 7:12808-12808(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAU99748.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BDGG01000005; GAU99748.1; -; Genomic_DNA.
DR   STRING; 947166.A0A1D1VMM4; -.
DR   Proteomes; UP000186922; Unassembled WGS sequence.
DR   InterPro; IPR028089; DUF4455.
DR   InterPro; IPR027914; DUF4456.
DR   PANTHER; PTHR21444; COILED-COIL DOMAIN-CONTAINING PROTEIN 180; 1.
DR   PANTHER; PTHR21444:SF14; COILED-COIL DOMAIN-CONTAINING PROTEIN 180; 1.
DR   Pfam; PF14643; DUF4455; 1.
DR   Pfam; PF14644; DUF4456; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000186922}.
FT   DOMAIN          113..505
FT                   /note="DUF4455"
FT                   /evidence="ECO:0000259|Pfam:PF14643"
FT   DOMAIN          1133..1229
FT                   /note="DUF4456"
FT                   /evidence="ECO:0000259|Pfam:PF14644"
FT   REGION          516..546
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          572..599
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          970..1014
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1030..1053
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1065..1089
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        518..532
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        970..998
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1072..1086
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1435 AA;  161163 MW;  16732AF42BFEB013 CRC64;
     MGDKENQEVA FLVQLLPDNY APSKDFTGIS TRIYERRKAF FGDQSSLLCK ELDIVGIEIE
     EKLTCCLKTL NNFIALNEAE LDKLASDSDP RDRPVNEQEA YGQGARFSLA EFDECTKRAK
     ELIKCRRDLI EQTQAVVESL ENHRAKEITK LFDVYVPRIL EGSHLLQEDA CRIMEQEMLA
     INQVILRNRR AYIALFEQLS AQAAYREKAC VETFKLHKLE WKELEVRRAI EKMGEALESH
     CKLDQSHVDA LLEPTRKYQE DLAWKKAGIV AELENLVPPA VTVSKCRKWV EDMEAVISEI
     YDTALEGVLK VRKYIEDRHL NYFDEVVKLA DLLKKNLQFS GEDIRFSFAE PCLFMSASRQ
     AQFDNDLQYY TWELNVKMDE EIRDVQSVFG FCHGATWHWE LHLTSVAKAE TFLDAQLEKQ
     RTLLKTMYDA KTAPKLRTIL EALRRAGTSA TVVTQQTAAG SAAKEVDGQL RDSWKKSLTY
     FGSYPSIVRV LMKGYEERLC AYMQVSMKKS IVAPAIEPFS PSQPPPPPKT DLNSKPTGRK
     LPDIPVDGEE KASLLSFGIT PADEENLGIR MKGLPIFPDD PRPKPLPETL STPSGVTFEP
     RPSTIEECFR FGVFSQALLP KGQAAPHTDS NQTLLIETAS QADMTKDVNV TTYVPKKLGL
     LNLDALVERS KMSSKLLVEE TKHGLTRKFL IHLAEQWTAL LTSSSNSFLE TKKEAFELEM
     QTRLRCSALR VTVFVEAVAR QRLEELTAHE DAYKDMETAV TTAIAELRTA DLAGINQKLN
     DRLTGVKDTL AVIEKGLLNA SRQAQIDQLK KRAQMFQDGG NYSPDEAKKF EQLFGKLIEK
     TAQGEKSFGT ECQQIELKRK TAVDMLVNKS MEKVPAHETD VEAVRVLTGI LARAQAEIKK
     HAALVNTEYA DVKGKMNYLR GVLAALRRNV TTAEIDADNV LLKLTGLLQE TRACCGQLGC
     IGSTWPVPAT SSVPETPKSP TAAPRNIASA QSARSAKGAN PPQLPPTEPA LVRQPTVTSF
     LLGSTRRSKI GAPLKAHPPV PTDFQLSTSD GPVPLVQPRI PVPMDGRPIT SSAPKTAPSS
     AVGLKGNDSL TEKKGAKSLE KYNVFGDTVL PGARTFLERV HVVCWQVLDE SLTASKAYHQ
     ARGTRPVTRP NLIPNSLEET VERLCRKLLN YLTQSEEFAA LMADRYREMA SGLMDLIVDL
     APLIFRHLLG RFFQELVLKS KLIKDKYGDD CRRISDARQD IDDLGIPIQL IRQNDIQELL
     KFFVASNKAD WLNELQTLSE DFLRKLKSAI EKLFEAADLL ITSEELQTPV APPTLTICAQ
     SRRSVVSPVD DPRRSTVGQT WKAFDISGIV EQPDETLCFC DISCEKTTLA HLAVDDARHR
     IFSEFLQQFD IRKEETAFFD RVPYKKPEAE QKECVESQLK RLEILDKIHN VKQRI
//