ID A0A1D1VPH0_RAMVA Unreviewed; 786 AA.
AC A0A1D1VPH0;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=DEP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=RvY_13365-1 {ECO:0000313|EMBL:GAV02851.1};
GN Synonyms=RvY_13365.1 {ECO:0000313|EMBL:GAV02851.1};
GN ORFNames=RvY_13365 {ECO:0000313|EMBL:GAV02851.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAV02851.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAV02851.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAV02851.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAV02851.1}.
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DR EMBL; BDGG01000008; GAV02851.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1VPH0; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR InterPro; IPR004776; Mem_transp_PIN-like.
DR PANTHER; PTHR22829; DEP DOMAIN PROTEIN; 1.
DR PANTHER; PTHR22829:SF5; INTEGRAL MEMBRANE PROTEIN GPR155; 1.
DR Pfam; PF03547; Mem_trans; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186922};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 485..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 525..545
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 707..729
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 744..763
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 786 AA; 88004 MW; 13701D6FDDD5571A CRC64;
MDSALMHDAT HPDHHSHTHP YNTTSSDFGP ASHLFPAILQ VFVVIFTGYA TGRAALISET
DSHGLNTFVS RFALPCMLFR AMATMNLSIV NWTMFTSILL SKSVVFFTVL VLSLVLSSKP
RQYGRAGIFA IAATQSNDFA LAFPIVDALY GRTHPELVPY IYLLGSVSLL ILNPIGFCFL
EFEKERKNRS LQQGRQRQPK RRWLRTGIHV LWSICSNPIN AMTFVGVLAN FAFERHIPEV
LDKILAAFAM TFSTTALFHL GLKMVGRIKQ FTGFRLVVPA LLILAKLLFL PLVSRAVIGH
LQPGRSSNET EDYANFGFLY GSIPMTPTVF VFSTQYDEQV DIVGTALVLG TFISGPWMFI
SAQMLSIQSF NIARYTSILA TTQMQVGAFG LLCVMWTVVI MMVNGRWRRI PHIFVMGLLS
FQFLSCLGML LWRLSENSDS PWQHYAQFSV FLLGVLGTRV WTAGIAVGLW VLNRWGLCAL
LRFRWILMFL CLGLPVLATV LTLALGEHSR ADLNPAFHYG QTQVLVSAVV LTVSLVLSLI
GIVGAQLSSS SKKKPTTRKF SVRTSSSSGE YSARQALIAN QDVELDDIPK REDRSIPDII
PEISGTPASE MEIVPFEEPQ QDADSYDAFD AAGLHPSPHS SQNVRLQRCP AEARHTSVQR
DLCKQLTQEY FVQDFRTTGK RRRPDRSTAG ECDPEVPEDH FEQNRHVVLV LFLATSMLVA
TFLCFWRMFV DNSNAGGVFI ELEFLDGVLV FGQGCVVMAI FGFDMRSPAW FSRIKRIFLN
WRSSHI
//
