ID A0A1D1VR04_RAMVA Unreviewed; 387 AA.
AC A0A1D1VR04;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 08-NOV-2023, entry version 21.
DE RecName: Full=MPN domain-containing protein {ECO:0000259|PROSITE:PS50249};
GN Name=RvY_14343-1 {ECO:0000313|EMBL:GAV03995.1};
GN Synonyms=RvY_14343.1 {ECO:0000313|EMBL:GAV03995.1};
GN ORFNames=RvY_14343 {ECO:0000313|EMBL:GAV03995.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAV03995.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAV03995.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAV03995.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAV03995.1}.
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DR EMBL; BDGG01000010; GAV03995.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1VR04; -.
DR STRING; 947166.A0A1D1VR04; -.
DR MEROPS; M67.A09; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR Gene3D; 1.20.58.80; Phosphotransferase system, lactose/cellobiose-type IIA subunit; 1.
DR InterPro; IPR000555; JAMM/MPN+_dom.
DR InterPro; IPR037518; MPN.
DR InterPro; IPR015063; USP8_dimer.
DR PANTHER; PTHR12947; AMSH-LIKE PROTEASE; 1.
DR PANTHER; PTHR12947:SF13; FI19924P1; 1.
DR Pfam; PF01398; JAB; 1.
DR Pfam; PF08969; USP8_dimer; 1.
DR SMART; SM00232; JAB_MPN; 1.
DR SUPFAM; SSF102712; JAB1/MPN domain; 1.
DR SUPFAM; SSF140856; USP8 N-terminal domain-like; 1.
DR PROSITE; PS50249; MPN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186922}.
FT DOMAIN 214..346
FT /note="MPN"
FT /evidence="ECO:0000259|PROSITE:PS50249"
FT REGION 153..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 387 AA; 43657 MW; 896A03E350E13296 CRC64;
MARTNVRTAK ERLKDLTDVA ESIHVDHKNE NLRRYFISSK QLYETAKYEA AHGNLQKAYM
LIMRFLDIYV TRLPKHPFYD NVPEDLRKPT KALWVKALDL GGQLKPKVLE EFEQIVRAEE
AELAQNDPRS NASGSANLDD LLHRINTLNE HNGPSAPYFE SPGVSWPKVQ SDPVSPDEAF
ANSFSGGLGP QALPLVDRRN KPRSRLPSDA LREVRVPSDL VDRFGAAASE NTSQKNIETC
GNLWGVRDQG AYIVTHVIIP KQKGTDSYCE DLDEGAAAEL AISENLIQLG WIHTHPSQTA
FLSSVDMHMQ HGYQIMLPEA IAIVLAPKFN DIGFFRLNDY GMEMIGQCRE GTNFHVHDES
YPLFERIKEG VVTDGTKQTK LEDFRLR
//
