ID A0A1D1VW64_RAMVA Unreviewed; 1019 AA.
AC A0A1D1VW64;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Myosin motor domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=RvY_13683 {ECO:0000313|EMBL:GAV03224.1};
GN Synonyms=RvY_13683.1 {ECO:0000313|EMBL:GAV03224.1};
GN ORFNames=RvY_13683-1 {ECO:0000313|EMBL:GAV03224.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAV03224.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAV03224.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAV03224.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAV03224.1}.
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DR EMBL; BDGG01000009; GAV03224.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1VW64; -.
DR STRING; 947166.A0A1D1VW64; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd00124; MYSc; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF550; MYOSIN-IIIB ISOFORM X1; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS50001; SH2; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000186922};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 25..777
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 887..982
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT BINDING 123..130
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1019 AA; 115783 MW; 869438BB272C39E9 CRC64;
MRVSCLTGIN WNNPYKMGSV LLVDFDVDDL TSVSLIDEEA IVSILRYRYR KHKTVTLIGE
IFLSLNPFGG RRQSFSGTVR KKACIRPSSQ GPSIATLSQR IYRKLTKSTV EPLSRAQCCV
FSGDSGSGKT EASKTFLRLL AKCPGRGDLE AKIIAFNPLL EAFGNAKTSL NNNSSRFGKH
IRLNFDSSGK VLGATLSGYL LEKCRLTRQN PGESNFHIFH LLFSSLSDQK LQKLKLDRFT
RYRYLPGLGR KTAVGPLTSQ PSCAANGMLA EMVCAAGFSK REQKFMTVVL AAVLSIGNIR
FGEDPGGSTP FVAQTEVYLR NVSELLELDA SNFRNQLQNL EIYSRGEIIS RPYTKAEAED
CRDSIARALY SRLFSWIIHR INQDLTCGLP SRTEDQHNVG ILDIFGFENL TCNSFEQLLI
NLTNEQLHQL FNFKIFKQEQ QDYEDEGLDR NLIAYNDNAN ILKLFLDRPI GLLSLIDEES
HFPRGSDRTL AEKFEHHFRR NPLFQCSIQP IANASSTYSL DEKLSTSFSI RHFAGEVVYE
IEGFLEKNRD SLPGTFIKGG GTQTETKMTF VADRIALVFQ TSRNPLVSLL FQAIISRTGS
FMFDDKEATP GASRTSGHPG RSTRKRLTLG YQFRGSLLAL IDQLKASDTS FVRCIRPNKE
QKPGKFDDAY VLTQVSGPHL RNFLFNIPVL FFRLKLRNSG VLETVWLRRQ GFPYRPSFNE
FGSRFRGLLN EPHDDLLTLI DSSLLHYGNS SWHLGKTRVC IKYEVAEDLA RRIALRDKAA
RTIQRVFRKY RRCLQMMRKQ ERVKQPEVTA CPPLYATSLH IARGVYTGQD TPETHPDDSA
YSPSEHEYAY ADADQVCQWF KDCVYDQLGP QKNRRVVQIT RKNVPTWWFD HLTRQEAEDL
LRAKSAGTFL VRGTKDTPSV LVLSFRATPS SKCCRHYLID LADEKTFAVR GEKITHPSLP
DLLNYYRQNP LSNYDGYLTI PYGQEIPIQK HTSATYDHYM PPNIMNQSRK KTQPAVKFP
//
