ID A0A1D1W3U6_RAMVA Unreviewed; 383 AA.
AC A0A1D1W3U6;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Alpha-carbonic anhydrase domain-containing protein {ECO:0000259|PROSITE:PS51144};
GN Name=RvY_17267-1 {ECO:0000313|EMBL:GAV07433.1};
GN Synonyms=RvY_17267.1 {ECO:0000313|EMBL:GAV07433.1};
GN ORFNames=RvY_17267 {ECO:0000313|EMBL:GAV07433.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAV07433.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAV07433.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAV07433.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- SIMILARITY: Belongs to the alpha-carbonic anhydrase family.
CC {ECO:0000256|ARBA:ARBA00010718}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAV07433.1}.
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DR EMBL; BDGG01000015; GAV07433.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1W3U6; -.
DR STRING; 947166.A0A1D1W3U6; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0004089; F:carbonate dehydratase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00326; alpha_CA; 1.
DR Gene3D; 3.10.200.10; Alpha carbonic anhydrase; 1.
DR InterPro; IPR001148; CA_dom.
DR InterPro; IPR036398; CA_dom_sf.
DR InterPro; IPR023561; Carbonic_anhydrase_a-class.
DR PANTHER; PTHR18952; CARBONIC ANHYDRASE; 1.
DR PANTHER; PTHR18952:SF266; CARBONIC ANHYDRASE 2, ISOFORM A; 1.
DR Pfam; PF00194; Carb_anhydrase; 1.
DR SMART; SM01057; Carb_anhydrase; 1.
DR SUPFAM; SSF51069; Carbonic anhydrase; 1.
DR PROSITE; PS51144; ALPHA_CA_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000186922}.
FT DOMAIN 70..347
FT /note="Alpha-carbonic anhydrase"
FT /evidence="ECO:0000259|PROSITE:PS51144"
SQ SEQUENCE 383 AA; 42503 MW; A63B58CCAC5AC048 CRC64;
MKEACRKFSD AEPFPQVSKV CRTSTYTKSM KTPNSFIEPA ALQLLLSISV VCNLEPVLGV
PSQEIVRANV PWGYGNNSGG GYLGPDYWTN LPGGTSCGGS RQSPINFVTM SATRRNYEKD
RLFFDKHGKS PIDEKWTFVN NGHSVQLTTF YKAGERPELQ QNSLNGIYVF DQVHFHWGSD
DKFGSEHLVD GSAAVLELHI VHSLRNASNE EINQRRDGLA VIGILFEIGN FDNPKLESFV
RNLERVAQPG SSINNAVLAG HTLKDLIPSN KTFFRYMGSL TTPPCTENVV WTVFTQKQKI
SLDQLAVFRT VLANNELEHN ATVSPVPVSD NYRPPQPLNG REVFLFVDGA SSLSICQKLL
ALITLLDSVI NLLYSRKVFG SSI
//
