ID A0A1D1W9Y9_RAMVA Unreviewed; 1241 AA.
AC A0A1D1W9Y9;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=PHD-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=RvY_17756-1 {ECO:0000313|EMBL:GAV07989.1};
GN Synonyms=RvY_17756.1 {ECO:0000313|EMBL:GAV07989.1};
GN ORFNames=RvY_17756 {ECO:0000313|EMBL:GAV07989.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAV07989.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAV07989.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAV07989.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAV07989.1}.
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DR EMBL; BDGG01000016; GAV07989.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1W9Y9; -.
DR STRING; 947166.A0A1D1W9Y9; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0016589; C:NURF complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd15559; PHD1_BPTF; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR038028; BPTF.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR028941; WHIM2_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45975; NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF; 1.
DR PANTHER; PTHR45975:SF2; NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF; 1.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF15613; WSD; 1.
DR SMART; SM00571; DDT; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000186922};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 173..233
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT DOMAIN 324..371
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 1..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 489..553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 880..936
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1122..1147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..131
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 489..518
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 519..534
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 881..906
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1241 AA; 141442 MW; B203974052CB76D8 CRC64;
MPRARSQRAS QVQVVTPKST RKTATARKNH HVEEEEENES GSDVESPSAL TASDYRKPRS
SARAKRAATN NRPPPPTSAR SRRGRKVSES SDDEEEPPVS EEESSSDEES EEEDAEADAS
FEDPDDGDFN AEEGDASQKR TFIPKDRDPV YIQNREIPPL VLPPSSEDLI LLNNLLLQAL
GVYEILRRFF QGLQLTPFRF EDFCCAVTAE ENSRLIAEIF SAVIRLLVRD TESSGFWLAP
HDEKDSIYLP VACLDEVTWP EMLRMYLQSS PEYKDGLKIV EQSSFPCVSA KNKLDLLEMV
SSALLRLPGV IRSALTADFV ISHEEHCRNC QRPGDLICCE LCPATYHLEC SVPPLKEIPE
GEWVCHICRL NQIPGVSDCV SEVEKQNLHM RIEPVGLDRH GRRFTFLARR LFVYEEDESR
VWYYSTLPQF EQVLDLMDPE DLEKELCEAI DELRDEVENH FDVTQKLTKK YSSGRAIYLD
QANATIAEER KRREAEKAKK DEEDKKGKDS KEDIVVKEEM GTSSSSSTEP LSKDCSLAKQ
EGVEPGPKIA TRTRTGALAA KSYSDSLLKN AKDVTTILVP PHIDGSNTFD LLKTAGPSYK
LGVEGLFRLY KNMFKDNPFA QDKAQRQDER DRKRHLGTKY SLNAEKNTPG EFKWTGLKLG
ITKTLITTIK TTLMIELEKS IHPSFFHPTW KESRKMWQRE VEEAGTPEKL ALALIRFESS
CRPCIFMPSW HENMGCVKWC KIVAPDREEL RNQERRRKRE DDEAVVRSAK RCYVSFVQGV
QHQIWKHKGE EFRLSGKGGV YWWSSRFGDE KEPQLERVTT PVEPQNPPVI EEDVIDISSA
LSSNSSLFSI QSNVKEKLDR IWAKENLFVK NIAVTETDTN DTVKGESENV PKAEDKPTEK
PEVKMEVDGG TLSAESTPAV NKLDEKKEPS EKPDLPLGLV GLKLNGLLEK VPKNGEKDQN
EKEEEAKKEV IPRVDNGPKV GLPPLLDFTR EEDLLDFYRL SQHDYFGLAL NGGLVEMGGF
KYDFKASPNW EYAHFPRPNM RTAWRFRTYS VRNWGGVALQ IRTIYAALRW EEMNTKPPQA
GRKITHDEHS TIYAELVRKR PSARNLEFPR YEYMVKRVVM PNKDNNYRSN QKSTPAREGL
RERRVDTPKS KDPYLLDSWV IEDELELWEI RSFYERVEHP PPEPPKVPPS ASIMVPAPST
SSVYPGVVRS NSGKPLVKVP AEGISKSFLL SYQHNCRVFS S
//
