ID A0A1D1WC72_RAMVA Unreviewed; 510 AA.
AC A0A1D1WC72;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Cytochrome P450 {ECO:0008006|Google:ProtNLM};
GN Name=RvY_19273-1 {ECO:0000313|EMBL:GAV09789.1};
GN Synonyms=RvY_19273.1 {ECO:0000313|EMBL:GAV09789.1};
GN ORFNames=RvY_19273 {ECO:0000313|EMBL:GAV09789.1};
OS Ramazzottius varieornatus (Water bear) (Tardigrade).
OC Eukaryota; Metazoa; Ecdysozoa; Tardigrada; Eutardigrada; Parachela;
OC Hypsibioidea; Ramazzottiidae; Ramazzottius.
OX NCBI_TaxID=947166 {ECO:0000313|EMBL:GAV09789.1, ECO:0000313|Proteomes:UP000186922};
RN [1] {ECO:0000313|EMBL:GAV09789.1, ECO:0000313|Proteomes:UP000186922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YOKOZUNA-1 {ECO:0000313|EMBL:GAV09789.1,
RC ECO:0000313|Proteomes:UP000186922};
RX PubMed=27649274; DOI=10.1038/ncomms12808;
RA Hashimoto T., Horikawa D.D., Saito Y., Kuwahara H., Kozuka-Hata H.,
RA Shin-I T., Minakuchi Y., Ohishi K., Motoyama A., Aizu T., Enomoto A.,
RA Kondo K., Tanaka S., Hara Y., Koshikawa S., Sagara H., Miura T.,
RA Yokobori S., Miyagawa K., Suzuki Y., Kubo T., Oyama M., Kohara Y.,
RA Fujiyama A., Arakawa K., Katayama T., Toyoda A., Kunieda T.;
RT "Extremotolerant tardigrade genome and improved radiotolerance of human
RT cultured cells by tardigrade-unique protein.";
RL Nat. Commun. 7:12808-12808(2016).
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAV09789.1}.
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DR EMBL; BDGG01000027; GAV09789.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D1WC72; -.
DR STRING; 947166.A0A1D1WC72; -.
DR Proteomes; UP000186922; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24300:SF385; CYTOCHROME P450 306A1; 1.
DR PANTHER; PTHR24300; CYTOCHROME P450 508A4-RELATED; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000186922};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 510 AA; 58427 MW; 6A985D0ABD7EC2E1 CRC64;
MIGFTLSFPS LLATVALLYA VYYWYRHRNI PGGPRGVPFI GYAPFFGRNP QDKFLTFKEK
YGKMFSIYLG PRLTIVLNDY EAVKEAFLGQ AEIFSGRSPG FVFEFLSLGE DGKTHGILLA
EGEKLKKTRR FVLQSLRDLG MGKKRIQISI LEEAAVLVDI FRKNADQPFN PLPTLTASVA
NVICALSWGR RYDHEDEDFK KILSGFDIIP TFLSQASVLL GYPMLRHLPG KLRRSWENLV
IAVRWNQKFT DGIIEEHINE YQEGEPRDYV DAFVKQQRAE VAAGVDIEND ESIFNKEELR
KTVGSFFGAG SETTTMTLYW AILFMAHHQV VQKRVQKEIA DNIPMGGPVT VEDKAKLPYV
EAVCREIQRC ANVTPLGVLR CNLEETTLLG YRIPKRSNIM VNFLAIFRDP ALWDEPSRFM
PERFLDKEGK LYEPPFFMPF SIGKRACIGE SLARMEIFLF FSNILQNFNI LPCEEFPLPS
LEEYTTGISC RPLPYKIRLT TRETDPFHRV
//
