ID A0A1D2I4Q6_9ACTN Unreviewed; 327 AA.
AC A0A1D2I4Q6;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=6-phosphogluconate dehydrogenase, NAD(+)-dependent, decarboxylating {ECO:0000313|EMBL:ODA69423.1};
DE EC=1.1.1.343 {ECO:0000313|EMBL:ODA69423.1};
GN Name=gntZ {ECO:0000313|EMBL:ODA69423.1};
GN ORFNames=APS67_006435 {ECO:0000313|EMBL:ODA69423.1};
OS Streptomyces sp. AVP053U2.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1737066 {ECO:0000313|EMBL:ODA69423.1, ECO:0000313|Proteomes:UP000054731};
RN [1] {ECO:0000313|EMBL:ODA69423.1, ECO:0000313|Proteomes:UP000054731}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AVP053U2 {ECO:0000313|EMBL:ODA69423.1,
RC ECO:0000313|Proteomes:UP000054731};
RA Olsen C.W., Carey S., Hinshaw L., Karasin A.I.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 6-phosphogluconate dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00008419}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODA69423.1}.
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DR EMBL; LMTQ02000064; ODA69423.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D2I4Q6; -.
DR OrthoDB; 9804542at2; -.
DR Proteomes; UP000054731; Unassembled WGS sequence.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
DR GO; GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR004849; 6DGDH_YqeC.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006114; 6PGDH_C.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR006184; 6PGdom_BS.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006183; Pgluconate_DH.
DR NCBIfam; TIGR00872; gnd_rel; 1.
DR PANTHER; PTHR11811; 6-PHOSPHOGLUCONATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11811:SF67; 6-PHOSPHOGLUCONATE DEHYDROGENASE YQEC-RELATED; 1.
DR Pfam; PF00393; 6PGD; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PRINTS; PR00076; 6PGDHDRGNASE.
DR SMART; SM01350; 6PGD; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00461; 6PGD; 1.
PE 3: Inferred from homology;
KW Gluconate utilization {ECO:0000256|ARBA:ARBA00023064};
KW Oxidoreductase {ECO:0000313|EMBL:ODA69423.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054731}.
FT DOMAIN 160..308
FT /note="6-phosphogluconate dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01350"
FT REGION 287..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 327 AA; 34970 MW; 25A83DF684270F71 CRC64;
MQIGLVGLGR MGGNMRERIR AAGHTVVGYD TRPDLSDVAH LSDLVDRLDG PRAVWVMVPA
GAVTQHVIDQ LGSLLKPGDT VVDGGNSRWT EDEKHAKELG ARGIGFVDAG VSGGVWGLEN
GYALMVGGDE EHVERLKPIF DALKPEGPYG YVHAGRVGAG HFAKMVHNGI EYAMMQAYAE
GWELLEKVDS VDNVREVFRS WQDGTVIRSW LLDLAVDALD EDAHLEKLRG CAEDSGEGRW
TVEAALDNAV PLPAITASLF ARFSSRQEDS PQMKMVAALR RQFGGHAVAS AGTSTDRPDQ
GGHGSPEGGG SRVAGEVRAE PGSPDEV
//
