ID A0A1D2IDG5_9ACTN Unreviewed; 328 AA.
AC A0A1D2IDG5;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=DNA polymerase III subunit epsilon {ECO:0000313|EMBL:ODA72546.1};
DE EC=2.7.7.7 {ECO:0000313|EMBL:ODA72546.1};
GN Name=dnaQ {ECO:0000313|EMBL:ODA72546.1};
GN ORFNames=APS67_003172 {ECO:0000313|EMBL:ODA72546.1};
OS Streptomyces sp. AVP053U2.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1737066 {ECO:0000313|EMBL:ODA72546.1, ECO:0000313|Proteomes:UP000054731};
RN [1] {ECO:0000313|EMBL:ODA72546.1, ECO:0000313|Proteomes:UP000054731}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AVP053U2 {ECO:0000313|EMBL:ODA72546.1,
RC ECO:0000313|Proteomes:UP000054731};
RA Olsen C.W., Carey S., Hinshaw L., Karasin A.I.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODA72546.1}.
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DR EMBL; LMTQ02000016; ODA72546.1; -; Genomic_DNA.
DR RefSeq; WP_042166468.1; NZ_LMTQ02000016.1.
DR AlphaFoldDB; A0A1D2IDG5; -.
DR OrthoDB; 190275at2; -.
DR Proteomes; UP000054731; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProt.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd06127; DEDDh; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR006054; DnaQ.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR NCBIfam; TIGR00573; dnaq; 1.
DR PANTHER; PTHR30231; DNA POLYMERASE III SUBUNIT EPSILON; 1.
DR PANTHER; PTHR30231:SF4; PROTEIN NEN2; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF00929; RNase_T; 1.
DR SMART; SM00292; BRCT; 1.
DR SMART; SM00479; EXOIII; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleotidyltransferase {ECO:0000313|EMBL:ODA72546.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054731};
KW Transferase {ECO:0000313|EMBL:ODA72546.1}.
FT DOMAIN 22..186
FT /note="Exonuclease"
FT /evidence="ECO:0000259|SMART:SM00479"
FT DOMAIN 244..322
FT /note="BRCT"
FT /evidence="ECO:0000259|SMART:SM00292"
FT REGION 206..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 328 AA; 35754 MW; 18801FDED8AA9233 CRC64;
MLEDLTTEAS SPGAWPAAYP QGYAVVDVET TGLARDDRII SAGVYQLDAR GEVEDHWYTV
VDPERDPGPV WIHGLTSESL EGAPLFADIA GEFATRLEGR VLVAHNAVFD WQMIAREYAR
ARAQAPVKQR LCTIALSKEL ALPLPNHRLE SLAAHFGVVQ RRAHHALDDA RVLAEVFRPS
LRTAAARGVR LPLLECLPLT EWTDRPRLGQ QAGHGGGHRP AGWRTSRKRP ACPYPNPGRY
APDRPLKQGM RVAFSGDTSV ERDLLEDRAT EAGLHVATSI SRLTSLLVTN DPDSGTSKVV
KARQYGTPVV DEAAFGQLLG DVEPASEG
//
