ID A0A1D2KMW3_BROTH Unreviewed; 425 AA.
AC A0A1D2KMW3;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Nucleotide sugar dehydrogenase {ECO:0000313|EMBL:ATF26550.1};
GN ORFNames=CNY62_09185 {ECO:0000313|EMBL:ATF26550.1};
OS Brochothrix thermosphacta (Microbacterium thermosphactum).
OC Bacteria; Bacillota; Bacilli; Bacillales; Listeriaceae; Brochothrix.
OX NCBI_TaxID=2756 {ECO:0000313|EMBL:ATF26550.1, ECO:0000313|Proteomes:UP000243591};
RN [1] {ECO:0000313|EMBL:ATF26550.1, ECO:0000313|Proteomes:UP000243591}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BI {ECO:0000313|EMBL:ATF26550.1,
RC ECO:0000313|Proteomes:UP000243591};
RA Paoli G.C., Wijey C., Chen C.-Y., Nguyen L., Yan X., Irwin P.L.;
RT "Complete Genome Sequences of Two Strains of the Meat Spoilage Bacterium
RT Brochothrix thermosphacta Isolated from Ground Chicken.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; CP023483; ATF26550.1; -; Genomic_DNA.
DR RefSeq; WP_069126540.1; NZ_RSDU01000007.1.
DR AlphaFoldDB; A0A1D2KMW3; -.
DR KEGG; bths:CNY62_09185; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000243591; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000243591}.
FT DOMAIN 316..417
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 425 AA; 47075 MW; F8E1387CC9B477F3 CRC64;
MKKDNLKLGV LGLGYVGLPV AVAFGKKMPV MGLDVNQKRI EQLKHTHDET GEVTDEDLLS
TNIDFTSDAK RLKECNFIIV AVPTPINESN QPDMRILHKA SKMIGQNIQK GTTVVFESTV
YPGATEEECA PIIEQWSGLV SGKDFFIGYS PERINPGDKT HTFTTILKIV SGQNEQTTER
VADVYSSVVT AGVFKASSIK VAEAAKVIEN TQRDLNIALM NELSQIFHEL NIDTQEVLEA
AGTKWNFLKF EPGLVGGHCI GVDPYYLAHK AESVGYHPEV ILAGRRVNDS MAQYVGQSIV
KELLKQKKHL GCLKVSVLGL TFKENVPDIR NSKVADLIQE LEEYGIEVLS FDPLADADEI
YKEYKIEMAN YDQLTESDVV ILAVPHDVLL TEDGAPVKKL LKDETSMLVD LKKGLEKTAE
HSWSL
//
