ID A0A1D2N3E6_ORCCI Unreviewed; 994 AA.
AC A0A1D2N3E6;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Tyrosine-protein phosphatase non-receptor type 14 {ECO:0000313|EMBL:ODM99807.1};
GN ORFNames=Ocin01_06872 {ECO:0000313|EMBL:ODM99807.1};
OS Orchesella cincta (Springtail) (Podura cincta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Entomobryoidea; Orchesellidae; Orchesellinae; Orchesella.
OX NCBI_TaxID=48709 {ECO:0000313|EMBL:ODM99807.1, ECO:0000313|Proteomes:UP000094527};
RN [1] {ECO:0000313|EMBL:ODM99807.1, ECO:0000313|Proteomes:UP000094527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Mixed pool {ECO:0000313|EMBL:ODM99807.1};
RX PubMed=27289101; DOI=10.1093/gbe/evw134;
RA Faddeeva-Vakhrusheva A., Derks M.F., Anvar S.Y., Agamennone V., Suring W.,
RA Smit S., van Straalen N.M., Roelofs D.;
RT "Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors
RT in the Genome of the Collembolan Orchesella cincta.";
RL Genome Biol. Evol. 8:2106-2117(2016).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC receptor class subfamily. {ECO:0000256|ARBA:ARBA00009649}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODM99807.1}.
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DR EMBL; LJIJ01000254; ODM99807.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D2N3E6; -.
DR STRING; 48709.A0A1D2N3E6; -.
DR OMA; VGEFRIT; -.
DR OrthoDB; 3108587at2759; -.
DR Proteomes; UP000094527; Unassembled WGS sequence.
DR GO; GO:0071944; C:cell periphery; IEA:UniProt.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR GO; GO:0048666; P:neuron development; IEA:UniProt.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13188; FERM_C_PTPN14_PTPN21; 1.
DR CDD; cd17099; FERM_F1_PTPN14_like; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR041782; PTPN14/21_FERM_C.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45706:SF1; PEZ, ISOFORM A; 1.
DR PANTHER; PTHR45706; TYROSINE-PROTEIN PHOSPHATASE; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR Pfam; PF00102; Y_phosphatase; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SMART; SM00194; PTPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS50057; FERM_3; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Receptor {ECO:0000313|EMBL:ODM99807.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000094527}.
FT DOMAIN 21..313
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT DOMAIN 732..987
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 905..978
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 584..644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 683..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 598..644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..698
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 994 AA; 109275 MW; FAF6CF3FF06CEE67 CRC64;
MPLKILKRTS KQYNVVSKST FVISVELLDN GIMECTLDAD STGRDCLLNI SQRLGLHQPE
FFGLRYISRG VPPRQRWVEL DKPLKKQLEK NAQDSQLSLG VIFYVSDVTV LKDEMTRYHY
FLQLKSDIID GKLNCNIEQA ISLAAYSLQA EFGDYDPERH TVEYLRDFAI LPKDLTSGQK
FPDINIDVLY EAVARQYGSL IGFPPPLSEI YYIMVAQQLD GYGQEAYPAK DDSGNDVLIC
VSANGLVIRR RDWTHIAAFR WTDVKSIVGH KRSFVIETVQ SQRPVQFQFS DAEVAKYVRK
MCILQEKFFK DHIASCSENM RTVSNGTYTI TQPDTMEGAQ PSSSAASSQM VGLRATPDLI
APSLARSVAG SQYSLNSSAV NSNLLNGRNL SSSGLNLHLL QQQLHQTQAA IAATNSHCVN
PSLQELSAAC GGTSSNLVHN GSIGTVSSLA ETSIVNAIHS AHLPNVASSS LTNVGSLPLQ
INVANNVDHG QLKALLPAYR QAPDYNTAVQ IKYGGPVIQS LPVGDASQEA LYENQRKVSI
DQDEPIYQNE IVSQIHSLEL RDSQISSAPE PVVAVPNASP PEENVYIFKP PPPYPGNGAS
GSSSSSNLDI SKKHVSSENT PGLTKDHSHS QSIKMGTSLS RVPPSDMQAV KSVSAVSIVS
AEVHKAPLGR DTNCSSMENT SSVSISAKST SSLPKTNGLL KEGNGMRKSS ANVVQNENKP
GHLFGKPIDP NILREFQAIP KVKSNANFAT ALRRENAKRN RCPEVLPYED NTVRLHPTRA
NPLGFVNASP LMAHISGRDW KYMVGQIPLP GNAPAVWQLI WEANIKIIAV LERDSSALFY
PENGSSIPLN DFQVVESKAE RRGSASIARE YNLVYLPKKK QRKVWILPYE DEWKDDVPVH
TEHFLCFLEE VNSIQRKLND TSPLLVLCGT GAGRSGVLIL ADLLLHAADS GHKLRCDTLL
NELRTQRMAL VSTPSQYAFV LHTLAEYLAR SRLI
//
