ID A0A1D2N4D9_ORCCI Unreviewed; 364 AA.
AC A0A1D2N4D9;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 22-FEB-2023, entry version 19.
DE SubName: Full=Bifunctional nitrilase/nitrile hydratase NIT4B {ECO:0000313|EMBL:ODM99795.1};
GN ORFNames=Ocin01_06889 {ECO:0000313|EMBL:ODM99795.1};
OS Orchesella cincta (Springtail) (Podura cincta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Entomobryoidea; Orchesellidae; Orchesellinae; Orchesella.
OX NCBI_TaxID=48709 {ECO:0000313|EMBL:ODM99795.1, ECO:0000313|Proteomes:UP000094527};
RN [1] {ECO:0000313|EMBL:ODM99795.1, ECO:0000313|Proteomes:UP000094527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Mixed pool {ECO:0000313|EMBL:ODM99795.1};
RX PubMed=27289101; DOI=10.1093/gbe/evw134;
RA Faddeeva-Vakhrusheva A., Derks M.F., Anvar S.Y., Agamennone V., Suring W.,
RA Smit S., van Straalen N.M., Roelofs D.;
RT "Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors
RT in the Genome of the Collembolan Orchesella cincta.";
RL Genome Biol. Evol. 8:2106-2117(2016).
CC -!- SIMILARITY: Belongs to the carbon-nitrogen hydrolase superfamily.
CC Nitrilase family. {ECO:0000256|ARBA:ARBA00008129}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODM99795.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LJIJ01000255; ODM99795.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D2N4D9; -.
DR STRING; 48709.A0A1D2N4D9; -.
DR OrthoDB; 3470537at2759; -.
DR Proteomes; UP000094527; Unassembled WGS sequence.
DR GO; GO:0000257; F:nitrilase activity; IEA:UniProt.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR CDD; cd07564; nitrilases_CHs; 1.
DR Gene3D; 3.60.110.10; Carbon-nitrogen hydrolase; 1.
DR InterPro; IPR003010; C-N_Hydrolase.
DR InterPro; IPR036526; C-N_Hydrolase_sf.
DR InterPro; IPR000132; Nitrilase/CN_hydratase_CS.
DR InterPro; IPR044149; Nitrilases_CHs.
DR PANTHER; PTHR46044:SF1; CN HYDROLASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46044; NITRILASE; 1.
DR Pfam; PF00795; CN_hydrolase; 1.
DR SUPFAM; SSF56317; Carbon-nitrogen hydrolase; 1.
DR PROSITE; PS50263; CN_HYDROLASE; 1.
DR PROSITE; PS00920; NITRIL_CHT_1; 1.
DR PROSITE; PS00921; NITRIL_CHT_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000094527}.
FT DOMAIN 18..290
FT /note="CN hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS50263"
FT ACT_SITE 58
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10139"
SQ SEQUENCE 364 AA; 40184 MW; 3BE9A0C633AC8213 CRC64;
MAQLLDDRKD LIIPKKLVKV GVAQYSAVNF DLDKTLDRLE TIVKDASNKG VKLLVFPEAF
LPGYPHGGDL GVIFGNHALA GRKIYQLWHE SAVEIPGPAI TRLSKVAKDN SIFLVVGTIE
KEPTSSTLYC TVVFVSDEGL YLGKHRKLMP TNVERLTWGL GDGSTLPVYD SPAGKVGAVI
CWENYMPLLR TTMYTKGIQI YCAPTADNGD NWQYTMRHIA MEGRCFVLGC NQFTRRSDYP
ADSEFPNAIS DKDGDRVLCR GGSIIVSPLG EVLAGPNYSS EELLIAEIDL NDVIRGKYDL
DVVGHYNRPD IFTLYVNEKA NPGIVTKMQN LNCSEGGMNE DRGKCPHPCI KKGKGCEEKN
TEAK
//
