ID A0A1D2N9I3_ORCCI Unreviewed; 654 AA.
AC A0A1D2N9I3;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE RecName: Full=TNF family profile domain-containing protein {ECO:0000259|PROSITE:PS50049};
GN ORFNames=Ocin01_04796 {ECO:0000313|EMBL:ODN01901.1};
OS Orchesella cincta (Springtail) (Podura cincta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Entomobryoidea; Orchesellidae; Orchesellinae; Orchesella.
OX NCBI_TaxID=48709 {ECO:0000313|EMBL:ODN01901.1, ECO:0000313|Proteomes:UP000094527};
RN [1] {ECO:0000313|EMBL:ODN01901.1, ECO:0000313|Proteomes:UP000094527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Mixed pool {ECO:0000313|EMBL:ODN01901.1};
RX PubMed=27289101; DOI=10.1093/gbe/evw134;
RA Faddeeva-Vakhrusheva A., Derks M.F., Anvar S.Y., Agamennone V., Suring W.,
RA Smit S., van Straalen N.M., Roelofs D.;
RT "Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors
RT in the Genome of the Collembolan Orchesella cincta.";
RL Genome Biol. Evol. 8:2106-2117(2016).
CC -!- SIMILARITY: Belongs to the tumor necrosis factor family.
CC {ECO:0000256|ARBA:ARBA00008670}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODN01901.1}.
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DR EMBL; LJIJ01000135; ODN01901.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D2N9I3; -.
DR OrthoDB; 5358224at2759; -.
DR Proteomes; UP000094527; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005164; F:tumor necrosis factor receptor binding; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR006052; TNF_dom.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR Pfam; PF00229; TNF; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50049; TNF_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000094527}.
FT DOMAIN 499..652
FT /note="TNF family profile"
FT /evidence="ECO:0000259|PROSITE:PS50049"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 329..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 401..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..350
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 654 AA; 73512 MW; 539522F77440B1F3 CRC64;
MHVPLDLVHE THMHKSKGTI ITKDTKTTGS TTSDTGESQQ NEAAPVAGRP SAHLRPLSIL
SSLSFLKLRS SNAWTRTRQR ANGFQNELTE DEEVVVHFKR PVDCTSSPIE KTKRTELNSN
QKVPCNIQNA HQVKDCYANL LNSLPNVIHN ESSNKLYSKK VEAKAQHSRS GDNQVHLNKV
SHIYGSVENS VGFTGSFALH NSGRMCDQGR DLMTKQQSVS LHNLDDELNK PPRNQACTAG
VNHKSWWRVE GGSYLEVRAS HLLKLVCLLM VLTFVAAFTF HSRIRQLEAQ RTELIQELSG
VKMHLEILID RMDTVVSLAI PTKSSRAASF HSEQLEGDDS SMDAKEESDQ ILEKVGARNG
KRVLVKRSAA AGRTTKDLQF PSSSFSFNTL NNGSAAFDNL DDTWSPGVTP KDEKTKSPKG
NLRNKRLSRK VRKLVRKELK DFKAAQRIKL NTLKRKLSES RLQKRLLKLS CCIENTSSSH
NLSKYPGDAE IRQKTGVRAA YLQIDGTSVN IKKPKLELIG PWYLPESGDD IGFNDLWYNN
LALDSNGTTI IFEESGLYMI YSQVFYQLQR SPKSHGSPLG YRIYLKKSQN KRAIPIAECV
PSYPQTVYQT CFTQVTWFVE AQDEIYLEHF TDSLPMIDAL RSGQTFLGIV QLSM
//
