ID   A0A1D2NDM6_ORCCI        Unreviewed;       182 AA.
AC   A0A1D2NDM6;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=Calcium load-activated calcium channel {ECO:0000256|PIRNR:PIRNR023322};
DE            Short=CLAC channel {ECO:0000256|PIRNR:PIRNR023322};
GN   ORFNames=Ocin01_03338 {ECO:0000313|EMBL:ODN03347.1};
OS   Orchesella cincta (Springtail) (Podura cincta).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC   Entomobryomorpha; Entomobryoidea; Orchesellidae; Orchesellinae; Orchesella.
OX   NCBI_TaxID=48709 {ECO:0000313|EMBL:ODN03347.1, ECO:0000313|Proteomes:UP000094527};
RN   [1] {ECO:0000313|EMBL:ODN03347.1, ECO:0000313|Proteomes:UP000094527}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Mixed pool {ECO:0000313|EMBL:ODN03347.1};
RX   PubMed=27289101; DOI=10.1093/gbe/evw134;
RA   Faddeeva-Vakhrusheva A., Derks M.F., Anvar S.Y., Agamennone V., Suring W.,
RA   Smit S., van Straalen N.M., Roelofs D.;
RT   "Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors
RT   in the Genome of the Collembolan Orchesella cincta.";
RL   Genome Biol. Evol. 8:2106-2117(2016).
CC   -!- FUNCTION: Calcium-selective channel required to prevent calcium stores
CC       from overfilling. {ECO:0000256|PIRNR:PIRNR023322}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TMCO1 family.
CC       {ECO:0000256|ARBA:ARBA00006537, ECO:0000256|PIRNR:PIRNR023322}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ODN03347.1}.
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DR   EMBL; LJIJ01000077; ODN03347.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D2NDM6; -.
DR   STRING; 48709.A0A1D2NDM6; -.
DR   OMA; GMFGDFK; -.
DR   OrthoDB; 313692at2759; -.
DR   Proteomes; UP000094527; Unassembled WGS sequence.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032469; P:endoplasmic reticulum calcium ion homeostasis; IEA:UniProtKB-UniRule.
DR   InterPro; IPR002809; EMC3/TMCO1.
DR   InterPro; IPR008559; TMCO1.
DR   PANTHER; PTHR20917:SF0; CALCIUM LOAD-ACTIVATED CALCIUM CHANNEL; 1.
DR   PANTHER; PTHR20917; PNAS-RELATED; 1.
DR   Pfam; PF01956; EMC3_TMCO1; 1.
DR   PIRSF; PIRSF023322; DUF841_euk; 1.
DR   SMART; SM01415; DUF106; 1.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PIRNR:PIRNR023322};
KW   Calcium channel {ECO:0000256|ARBA:ARBA00022673,
KW   ECO:0000256|PIRNR:PIRNR023322};
KW   Calcium transport {ECO:0000256|ARBA:ARBA00022568};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Endoplasmic reticulum {ECO:0000256|PIRNR:PIRNR023322};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW   ECO:0000256|PIRNR:PIRNR023322};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR023322};
KW   Reference proteome {ECO:0000313|Proteomes:UP000094527};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR023322}.
FT   TRANSMEM        6..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        89..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   COILED          30..84
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   182 AA;  20709 MW;  1D87DC9EF06F3ACC CRC64;
     MWSDTFLIIF ISVVTAFFGE GVTWLMVYRT EKYQKLKLEV ERQCKKLEKR KEATGESVIV
     KNQKKKLERE EEKLKTNTRD LSLVKMKSMF AIGVAFTALL SIFNSIFDGR VVAKLPFIPL
     GFLQGISHRN LPGTDYTDCS FIFLYILCTM AIRQNVQKLL GFAPSRAVSK QSGNIFGPPP
     AK
//