ID A0A1D2NGF2_ORCCI Unreviewed; 2884 AA.
AC A0A1D2NGF2;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Probable ATP-dependent RNA helicase spindle-E {ECO:0000256|ARBA:ARBA00013352};
GN ORFNames=Ocin01_02355 {ECO:0000313|EMBL:ODN04338.1};
OS Orchesella cincta (Springtail) (Podura cincta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Entomobryoidea; Orchesellidae; Orchesellinae; Orchesella.
OX NCBI_TaxID=48709 {ECO:0000313|EMBL:ODN04338.1, ECO:0000313|Proteomes:UP000094527};
RN [1] {ECO:0000313|EMBL:ODN04338.1, ECO:0000313|Proteomes:UP000094527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Mixed pool {ECO:0000313|EMBL:ODN04338.1};
RX PubMed=27289101; DOI=10.1093/gbe/evw134;
RA Faddeeva-Vakhrusheva A., Derks M.F., Anvar S.Y., Agamennone V., Suring W.,
RA Smit S., van Straalen N.M., Roelofs D.;
RT "Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors
RT in the Genome of the Collembolan Orchesella cincta.";
RL Genome Biol. Evol. 8:2106-2117(2016).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC {ECO:0000256|ARBA:ARBA00008792}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODN04338.1}.
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DR EMBL; LJIJ01000047; ODN04338.1; -; Genomic_DNA.
DR STRING; 48709.A0A1D2NGF2; -.
DR OrthoDB; 21853at2759; -.
DR Proteomes; UP000094527; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR CDD; cd17917; DEXHc_RHA-like; 2.
DR CDD; cd18791; SF2_C_RHA; 2.
DR CDD; cd20379; Tudor_dTUD-like; 1.
DR Gene3D; 1.20.120.1080; -; 2.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 2.40.50.90; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR002999; Tudor.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF113; ATP-DEPENDENT RNA HELICASE TDRD9; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF00271; Helicase_C; 2.
DR Pfam; PF00567; TUDOR; 2.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00847; HA2; 2.
DR SMART; SM00490; HELICc; 2.
DR SMART; SM00333; TUDOR; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR PROSITE; PS51194; HELICASE_CTER; 2.
DR PROSITE; PS50304; TUDOR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Helicase {ECO:0000313|EMBL:ODN04338.1};
KW Hydrolase {ECO:0000313|EMBL:ODN04338.1};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000094527};
KW RNA-mediated gene silencing {ECO:0000256|ARBA:ARBA00023158};
KW Spermatogenesis {ECO:0000256|ARBA:ARBA00022871}.
FT DOMAIN 171..338
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 389..579
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1676..1847
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1921..2098
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 2441..2499
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 73..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1410..1556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1583..1642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..110
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1434..1493
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1517..1547
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1590..1636
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2884 AA; 326142 MW; 68225A995B50F9B0 CRC64;
MASNEGGKLP ITNFFGFGNK QLPKMVTPSS TMAMRQPDNL DGWSVSPPQE TENEFAYVKA
HAETRQQLIN NARFAGHRNE NFSSGSQVPE ERRERGRGRG HTRGRGGDRG RGASRGGGAS
RGNRSSVGKS IFGTVPDNRT SDLDVYLKYD FDKRMFDTSQ LVINRMREKI ITHLSENQIM
IIEGFTGCGK TTQVPQFILD DAVAHNEGCR IVVTQPRRIA AISVANRVGA ERNWRVGGLV
GYQVGMDKRV SDDTRLTYMT TGVLLQLLIA RKSLNEWTHI IIDEVHERDL DTDLLLLVIN
KLMVDTRNDA TKIILMSATL NRDKFASYFP LWDSQKDACA CVSVDLPNQY PVTEYYLDDV
ASLAGYQNIN MEGLEEPKVH PECYEIAEKI IEGLDMAEVK DLPGPGGSGN ARGAVLVFLP
GLLEIETFYK VLTEISSLRS ASDDPMKQTQ WQVLPLHSSI TNEEQQRVFI PAKKGYRKII
LATNIAESSI TVPDIKYVID FCLTKSLSCD RTTNYTCLRL EWASKNQCIQ RRGRCGRVAA
GLVYRMVTRK FYETLEQECQ PEMLKSSLES VVLQVKLLDM GTPENVLSWA VDPPSSSLIS
RAVANLKEIG ALTINAGGKY DVYDGDLTFV GRVLSRLPID IRLGRLILLG HVFDCLEETV
IIAAGLSVKT PFAYPYSKRL DAYLSKLNWT AQSFSDCMAL LNLYTNWYHR HQSRDFLGFA
DEKAWARTYF VQLTSLREMK VLVDELYKRL TLCGIELLPS SRGGEDQSLI LKLVIAGGFY
PNYFNRARPN PKDYQKEIFK DVAGKDPFSS VVFQGFPLEQ PGDLYKKTIV RHVAFQNSIP
SIEFHGSKVV VTFDSRGDRL GPICSAVYRA VKLRQLRHTI TFATPSRDEA YGMINSAKMK
MDLAEVVSSP RQLLMPSLQV RSFQAIITHI ESPMEFFIIR KVDEEAAREI VDTITKIRLS
LKGITRDLCF PGQLCIVFVK GKFFRARIDS EKYNGDELMV YLIDRGMTMW IRRNYVYRAD
RNVCDVDLHL KPALAIKCRL SGIRAAVRNG CVWTTEAQRA FENYCAQSKN QVFIDIYSIV
ECTIAAQIKN TEQSVSVNDV LVEKKYADVA PEQMASKENN NIRERVYADS KNELSTAFSA
LEVQQNKCVI PQRLMDPPII EKEPEQLAVL RGPHNPLEMV FTSLCRSAHM KQVITDGSST
NSVVLDQDPT NPSSRLLIAA NVAIAARSGN ILARETTVMP PIPGLCGLLS MLFCPKLEFR
VDPDYTTYTG CLTGLGIDPE NGQSVYRDHD MEVVFDTVID NRDIALVNSV RSSMNYILTE
RARHTDIQNL RIRLRRESLS LLERQRSSMD EVWPEQPHEW NMLDPARLRY ASKSKESGTV
FPLHPHVALE EKQEGIDVPM NRNMYFCESN AQGVHHGPPI KVEPGTSSSS REQSTSRKRP
RDSDEHSDDE GRPTIRIKTE PELYDHDEDF DEPKTPPVPR GFEEREVKQE VNDAGSNVDE
TIPQENERVR TNGAEPAAAQ AESSSQQGSS PFSGHKSKTT PGTSKAKEAT PIANFFSFGD
KPQMQATLPN SVKAEIQVKS ATLPQKAHYN SHTAEEETNY GGDDGKTKIK PIPLPMKKEG
SDSDASDDES SRPTDDSNPR ISRYFQRSNV YKKYPFDKRR VDPTRLAVYE KKSLILSQLE
VARVIIVEGF TGCGKTTQVP QYILDKCKED DRVCNIVVTQ PRKIAAISVA RRVCHEREWS
LGSVVGYQVG METKTDRNDT LLTFMTTGVL LQKLIGSKSL KEFTHIIIDE VHERDLESDL
LLLIIKKIMA ADRNGRESHV KLILMSATIN TRQFEDYFLF GDENEQIRPR VVKIPFIPQH
KVEELYLEDL LSHKTDLLET IRSNLDRNKA AIQEEIYDVA VNTIISLDNL ERSKNPDPRL
RGRNIYPTHR GAVLVFLPGI EEIRSLAKAL DTAQKDSPDN ADQDANFFKW TILTLHSSIT
SSDQDKVFQP SLPKYRKIIL STNIAESSVT VPDIAYVIDF CLTKSLCIDQ ATNYTTLRLM
WASQSQCVQR RGRTGRVAEG KAYRLVGRSF YHALDMQIEP EMRRSNLETV ILMCKRFDLD
SPVGLLTDAL DRPNLSGIER AISTLKELGA LTVEMKDKST GRLKYETCDG DLTFLGKIMS
HLPIPQQCTR LIMLGHAFGV MNEAVIIAAA LSGKTPFLSG FREQIDVYMR KMDHAQKSFS
DLFALYHLYQ HWICNFAESG DMSGRNKNFR ERAWAQGARV HLQALRDIKS TSEVLWERLK
RHNIKNSYVV SANADPMELT QEQGIFLKMA IAGAFYPNYF LRRRPDVKEF ERTANRDLNG
LDVHRTIFFK GWPQGLEGKF KDYEVQELQK WEGIRRSRRI NVCPKQVTLP PVRINQVKVQ
VQHIVSPSQF WVVFNINSGQ MQQIERSIHE NQYAITLPRS KCVPNGFCLA PFENVYYRAK
IIRVFNNGQS CLVYFVDYGN TNLVQTSCLN DFPPTLRTLG IHEMPCMAVE ARLSQLKPNT
IHGLHWSPEA VSRIKDFCSR AHQLEMKIYS INQSVVAGEL FGSGPDGKGR CSLNELLQMK
DKDVGGKQLG EPARETYLSE KNHERRVRGS FMDQEEENAV NYEQIGDPLD LDFIDPPREN
LQMPVSLKGP WSPLEMTFQA LVQSSNTKQV RIDNNSVNSV LLDHEPTAPT SRMLVAANVT
ITDKSQSITA RDSTVMAPVP GILSLVSMIF APKVELRVDP QLSRYTGVLC GCGVTPTNRD
LPVHPDNDME IVFDTEIDDD DIDLINKIRF QLNLILGSTG TVNIAACHKQ LGLDLVKLMQ
KQRNKIDEEI WPQEEYVWNR IDPAYLNNKI THSMTFKPQD IFQPHSKVFL NKVVTEEIKW
NLGY
//
