ID A0A1D2W4V4_9EURY Unreviewed; 549 AA.
AC A0A1D2W4V4;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Fumarate reductase subunit A {ECO:0000313|EMBL:OEC84571.1};
GN ORFNames=A9507_02075 {ECO:0000313|EMBL:OEC84571.1};
OS Methanobacterium sp. A39.
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobacterium.
OX NCBI_TaxID=1860100 {ECO:0000313|EMBL:OEC84571.1, ECO:0000313|Proteomes:UP000094736};
RN [1] {ECO:0000313|EMBL:OEC84571.1, ECO:0000313|Proteomes:UP000094736}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A39 {ECO:0000313|EMBL:OEC84571.1,
RC ECO:0000313|Proteomes:UP000094736};
RA Woodcroft B.J.;
RT "Validation of picogram- and femtogram-input DNA libraries for microscale
RT metagenomics.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEC84571.1}.
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DR EMBL; LZPM01000052; OEC84571.1; -; Genomic_DNA.
DR RefSeq; WP_069585570.1; NZ_LZPM01000052.1.
DR AlphaFoldDB; A0A1D2W4V4; -.
DR STRING; 1860100.A9507_02075; -.
DR Proteomes; UP000094736; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF51; SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PIRSF; PIRSF000171; SDHA_APRA_LASPO; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000094736}.
FT DOMAIN 9..389
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 442..538
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT ACT_SITE 285
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000171-1"
SQ SEQUENCE 549 AA; 60186 MW; FC0FDC67D36BD5B7 CRC64;
MEREVYECDV LIIGSGGAGC RAAIEASKYD LDIIIVSKGL TFKSGCTTLA EGGYNAVFGA
ADCADTVEAH FEDTLKGGGY LNDSNLVRIL VEEAPQRLIE LESYGALFDR QESGQINQRP
FGGQSYRRTC FQGDRTGHEM MLGLKDEVTK RGIKTMDEIM ITSLIMDENG RNVIGACGLS
LKDSKLEVFK AKSVILGSGG AGWLYPVTSN TLQKTGDGYF IAYNAGADLL DMEQVQFHPT
GMIHPESRKG VLVTEAVRGE GGILLNSEGE RFMEKYDPRK ELATRDVVAR AIYNEIREGR
GTAKGGVYLD VTHLPAEVIE EKLETMLAQF LDVGVDIRKE PMEVAPTAHH FMGGVRITEN
GETTVGNLFA AGEAAAGVHG ANRLGGNALA DTQVFGKRAG EAAAKNALDS ELLSNDAFVD
AEDARISGLI KDGTVYPFEI KKELEEVMWK DVAIIRNQEG LMSALKRIKE LKEMLPDMKV
PGGMDFNKDL QDALEAFVML DVAEIVTKAA FLRRESRGSH YREDYPETSD DWKKSIVFNK
SGRLKFIER
//
