ID   A0A1D2WAZ0_9EURY        Unreviewed;       399 AA.
AC   A0A1D2WAZ0;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:OEC87192.1};
GN   ORFNames=A9507_07715 {ECO:0000313|EMBL:OEC87192.1};
OS   Methanobacterium sp. A39.
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanobacterium.
OX   NCBI_TaxID=1860100 {ECO:0000313|EMBL:OEC87192.1, ECO:0000313|Proteomes:UP000094736};
RN   [1] {ECO:0000313|EMBL:OEC87192.1, ECO:0000313|Proteomes:UP000094736}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A39 {ECO:0000313|EMBL:OEC87192.1,
RC   ECO:0000313|Proteomes:UP000094736};
RA   Woodcroft B.J.;
RT   "Validation of picogram- and femtogram-input DNA libraries for microscale
RT   metagenomics.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OEC87192.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LZPM01000017; OEC87192.1; -; Genomic_DNA.
DR   RefSeq; WP_069583320.1; NZ_LZPM01000017.1.
DR   AlphaFoldDB; A0A1D2WAZ0; -.
DR   STRING; 1860100.A9507_07715; -.
DR   Proteomes; UP000094736; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08282; PFDH_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR42813:SF3; GLUTATHIONE-INDEPENDENT FORMALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000094736}.
FT   DOMAIN          26..136
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
SQ   SEQUENCE   399 AA;  43286 MW;  7DFFB553DC3BAD18 CRC64;
     MKAVVYKGPK KVEVKDVENP KISKPTDAII RITSSAICGS DLHMYDGETT FESGRTLGHE
     PMGVVEEVGD AVQLVKPGDR VVMPFNIACG FCLNCIQGMT NACLTLNREQ PGAAYGYVDM
     GPYEGGQAEY VLVPFADWAC LKLPGEPGDE FEDDFVLLAD IFPTSYYSTE LAHVSAGKAV
     AVFGAGPVGL LAAYSSVLKG AGEVYIVDDS DERLKRAESI GAIPINTDDG DPAQQIMEMR
     QNNKNLMESL RLGEEKTLGV DSAIDAVGFQ AYDRENPNQE KRNQVLMDIA NVINAGGHVG
     LIGVYPKENP AADNEDEKQG NIMFPLGKLW EKGITIGMGQ TPVKQLHVFL RNLIFDGKAK
     PSFIVSDRIS IEDAPQIYSQ FDKRDTVVKP VIKFGAAAK
//