ID A0A1D2X1Y4_9EURY Unreviewed; 488 AA.
AC A0A1D2X1Y4;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Sodium:calcium symporter {ECO:0000313|EMBL:OED29887.1};
GN ORFNames=NL43_05590 {ECO:0000313|EMBL:OED29887.1};
OS Methanosphaera sp. WGK6.
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanosphaera.
OX NCBI_TaxID=1561964 {ECO:0000313|EMBL:OED29887.1, ECO:0000313|Proteomes:UP000094737};
RN [1] {ECO:0000313|EMBL:OED29887.1, ECO:0000313|Proteomes:UP000094737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WGK6 {ECO:0000313|EMBL:OED29887.1,
RC ECO:0000313|Proteomes:UP000094737};
RX PubMed=27022996; DOI=10.1038/ismej.2016.41;
RA Hoedt E.C., Cuiv P.O., Evans P.N., Smith W.J., McSweeney C.S., Denman S.E.,
RA Morrison M.;
RT "Differences down-under: alcohol-fueled methanogenesis by archaea present
RT in Australian macropodids.";
RL ISME J. 10:2376-2388(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OED29887.1}.
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DR EMBL; JRWK01000009; OED29887.1; -; Genomic_DNA.
DR RefSeq; WP_069593062.1; NZ_JRWK01000009.1.
DR AlphaFoldDB; A0A1D2X1Y4; -.
DR STRING; 1561964.NL43_05590; -.
DR PATRIC; fig|1561964.3.peg.1109; -.
DR OrthoDB; 99721at2157; -.
DR Proteomes; UP000094737; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd10334; SLC6sbd_u1; 1.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR000175; Na/ntran_symport.
DR InterPro; IPR037272; SNS_sf.
DR NCBIfam; NF037979; Na_transp; 1.
DR PANTHER; PTHR11616:SF279; SODIUM-DEPENDENT SEROTONIN TRANSPORTER; 1.
DR PANTHER; PTHR11616; SODIUM/CHLORIDE DEPENDENT TRANSPORTER; 1.
DR Pfam; PF00209; SNF; 2.
DR PRINTS; PR00176; NANEUSMPORT.
DR SUPFAM; SSF161070; SNF-like; 1.
DR PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..478
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 488 AA; 53535 MW; 7DA33DA39112B595 CRC64;
MSENKQKWDS NLSFLFAMIG SAVGLGNIWR YPYVAYTNGG GSFLIPYIVS IICMGIPLLF
VEYGAGFKFK AGMSKIVREI NKKYEYLGWF ILTPTFFILT YYCCVVAWDL IYLPLSFTKG
WGASPDNFFT NIVLDAGNPG GLFHIAILVL CAVVIVWFIL WFISHRNLNE GVGKFNKIFI
PLLFVMMIII VLSAITLPGA SIGIAKLLTP NLSAIFDLNI WLAAFGQILF SLSVGMSIAL
AYASYLDDKT DLPKNALTVA IANSLFEIFT AIGVFAILGY MSTTHNIPID QLVSQGTGLA
FVVFPQIFNV MGTLGYIIGP LFFFCLLFAG LTSNISVIEP LALAISDKFA LSRSKAVTIV
CGAGFIISLI YTTSMGGDLL GIVDTFANNF GVVFNVILEI IIFAWIYGLE NIIPSINKNA
KFLKLGHKWT ILVKYVILVI VLCIWISGIV TTLLSGETLT VTVELILFIA LIGIPAVLTK
LPARNDDY
//
