ID A0A1D3DB91_9EIME Unreviewed; 819 AA.
AC A0A1D3DB91;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=tRNA-splicing endonuclease positive {ECO:0000313|EMBL:OEH80701.1};
GN ORFNames=cyc_04542 {ECO:0000313|EMBL:OEH80701.1};
OS Cyclospora cayetanensis.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Cyclospora.
OX NCBI_TaxID=88456 {ECO:0000313|EMBL:OEH80701.1, ECO:0000313|Proteomes:UP000095192};
RN [1] {ECO:0000313|EMBL:OEH80701.1, ECO:0000313|Proteomes:UP000095192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHN_HEN01 {ECO:0000313|EMBL:OEH80701.1,
RC ECO:0000313|Proteomes:UP000095192};
RX PubMed=27129308; DOI=10.1186/s12864-016-2632-3;
RA Liu S., Wang L., Zheng H., Xu Z., Roellig D.M., Li N., Frace M.A., Tang K.,
RA Arrowood M.J., Moss D.M., Zhang L., Feng Y., Xiao L.;
RT "Comparative genomics reveals Cyclospora cayetanensis possesses coccidia-
RT like metabolism and invasion components but unique surface antigens.";
RL BMC Genomics 17:316-316(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEH80701.1}.
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DR EMBL; JROU02000003; OEH80701.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D3DB91; -.
DR VEuPathDB; ToxoDB:cyc_04542; -.
DR VEuPathDB; ToxoDB:LOC34621064; -.
DR InParanoid; A0A1D3DB91; -.
DR Proteomes; UP000095192; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF525; HELICASE SENATAXIN-RELATED; 1.
DR Pfam; PF13086; AAA_11; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:OEH80701.1};
KW Hydrolase {ECO:0000313|EMBL:OEH80701.1};
KW Nuclease {ECO:0000313|EMBL:OEH80701.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000095192}.
FT DOMAIN 492..634
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 671..723
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT REGION 81..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 153..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 549..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 819 AA; 88519 MW; 419C08D378D56A3A CRC64;
MLARQVGTLG GRHAFLPRSR IDSKNLFKSV LRRQKHLTGG EGVCSATTAL SERSKQLLDI
RREAYREAAA ATAAAAAVRS PEGGGDAALS VAATKPKRRR LTEEGAEKAA ERAVAEKQRS
SARFQQRASA AVAAIGLPAE DRRPAVRLLS PSCAGTVGAS RDGGRRASEQ EQQIRQVQET
LQRDRRTWRQ QQRQAHETAR VALLRFLWSL LETDIFSLAS SPQEMSLAEA SAAAAARDSS
KRLQPQVAAL AAVSKAHPLP LRFDALQRLQ HLRQNRLRGQ RCVLNRLRNA GSQWTAATFS
VGTAAMAASA TAAAGGRYAD VYAAARAAAM GASSAATDTP VLRPGDLLLL IPETPFFNNG
EVVPTPASPI STAASAAQQK ETEEASSWCG RVINKRTIRP RNGYTIGVVE AWSTPEQRQE
GLTVRLLLGA SVSIAVEPQR LLKCTADAAA PVPGAADLLL QLRLQQHHMQ RVATNYRLNK
SQAAAVAGLI GAVDEIAERI LRDGLLDAST GDIVQPACLR IGTSNYPSCG LFRIINLLGG
DASPSNSSLA ASSVVSERSQ QPAHQSPQTK TEVMRLQLQN RLAEKRRLGD VLHRKRRGLQ
LRLGVLPRLV RRHLVASADI IFSTLSGCGS EILDPLCEDE SDVDFAAAGA PEGGTNIIDQ
RRGKKLISSP SSSSLSSDLH FACVIVDEAG QATEVASLIP LRLRCDRLFL FGDPLQLPPL
ICSFAAQAKG LGRSLMARLA LCCQQQEQKA WEEDEQAQTT QLQREVAFYF LATQYRMHPL
IVEFPEQAAS RLTTPEDRHH RNSSPLCLLS LPSAQFPLL
//
