ID A0A1D3DRI0_9ACTN Unreviewed; 447 AA.
AC A0A1D3DRI0;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Leupeptin-inactivating enzyme 1 {ECO:0000313|EMBL:OEJ94923.1};
GN ORFNames=J116_010925 {ECO:0000313|EMBL:OEJ94923.1};
OS Streptomyces thermolilacinus SPC6.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1306406 {ECO:0000313|EMBL:OEJ94923.1, ECO:0000313|Proteomes:UP000095329};
RN [1] {ECO:0000313|EMBL:OEJ94923.1, ECO:0000313|Proteomes:UP000095329}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SPC6 {ECO:0000313|EMBL:OEJ94923.1,
RC ECO:0000313|Proteomes:UP000095329};
RX PubMed=23868127;
RA Chen X., Zhang B., Zhang W., Wu X., Zhang M., Chen T., Liu G., Dyson P.;
RT "Genome Sequence of Streptomyces violaceusniger Strain SPC6, a Halotolerant
RT Streptomycete That Exhibits Rapid Growth and Development.";
RL Genome Announc. 1:0-0(2013).
CC -!- SIMILARITY: Belongs to the peptidase M28 family. M28A subfamily.
CC {ECO:0000256|ARBA:ARBA00005957}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEJ94923.1}.
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DR EMBL; ASHX02000001; OEJ94923.1; -; Genomic_DNA.
DR RefSeq; WP_023587109.1; NZ_ASHX02000001.1.
DR AlphaFoldDB; A0A1D3DRI0; -.
DR STRING; 1306406.J116_010925; -.
DR eggNOG; COG2234; Bacteria.
DR eggNOG; COG4935; Bacteria.
DR OrthoDB; 345880at2; -.
DR Proteomes; UP000095329; Unassembled WGS sequence.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:InterPro.
DR GO; GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd03876; M28_SGAP_like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR045175; M28_fam.
DR InterPro; IPR041756; M28_SGAP-like.
DR InterPro; IPR002884; P_dom.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR12147; METALLOPEPTIDASE M28 FAMILY MEMBER; 1.
DR PANTHER; PTHR12147:SF55; PEPTIDE HYDROLASE; 1.
DR Pfam; PF01483; P_proprotein; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS51829; P_HOMO_B; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..447
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008914721"
FT DOMAIN 328..447
FT /note="P/Homo B"
FT /evidence="ECO:0000259|PROSITE:PS51829"
SQ SEQUENCE 447 AA; 46298 MW; C97A8C66EC7E131F CRC64;
MTHSVSRIPR RTAAAAVLAL TGLLATAAPA ATAAPPAAAP ATARTAAAAP DIPLANVKAH
LTQLQSIATA NGGNRAHGRP GYKASIDYVK AKLDAAGFTT SVQQFTSNSA VGYNLIADWP
GGDPNQVLMA GAHLDSVSSG PGINDNGSGS AAVLESALAV SRAGLKPAKH LRFAWWGAEE
LGLVGSKYYV ANLPATERSK LSGYMNFDMI GSPNAGYFVY DDDPVIEKTF KDYFAGLGVP
TEIETEGDGR SDHASFKNVG VPVGGLFTGA SRTKTSAQAQ KWGGTAGQAF DRCYHSSCDT
TSNINDTALD RNSDALAHAV WTLSAGTTEP PAGDTYQNTS DVPIPDGGAA VTSPVTVSGR
TGNAPAALRV GVDIVHTWRG DLVIDLVAPD GTAYRLKNSS GGDSADNVRE TYTVDASVEA
ANGTWLLRVQ DVARYDTGYI NSFSLTF
//
