ID A0A1D3JJ80_PLAMA Unreviewed; 994 AA.
AC A0A1D3JJ80;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Replication factor C subunit 1 {ECO:0000256|ARBA:ARBA00020401, ECO:0000256|PIRNR:PIRNR036578};
GN Name=RFC1 {ECO:0000313|EMBL:SBT86436.1};
GN ORFNames=PMUG01_04012800 {ECO:0000313|EMBL:SBT86436.1};
OS Plasmodium malariae.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5858 {ECO:0000313|EMBL:SBT86436.1, ECO:0000313|Proteomes:UP000219813};
RN [1] {ECO:0000313|EMBL:SBT86436.1, ECO:0000313|Proteomes:UP000219813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR036578}.
CC -!- SIMILARITY: Belongs to the activator 1 large subunit family.
CC {ECO:0000256|ARBA:ARBA00006116, ECO:0000256|PIRNR:PIRNR036578}.
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DR EMBL; LT594625; SBT86436.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D3JJ80; -.
DR VEuPathDB; PlasmoDB:PmUG01_04012800; -.
DR OrthoDB; 6297at2759; -.
DR Proteomes; UP000219813; Chromosome 4.
DR GO; GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003689; F:DNA clamp loader activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd17748; BRCT_DNA_ligase_like; 1.
DR CDD; cd18140; HLD_clamp_RFC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR013725; DNA_replication_fac_RFC1_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012178; RFC1.
DR InterPro; IPR047854; RFC_lid.
DR PANTHER; PTHR23389; CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; 1.
DR PANTHER; PTHR23389:SF6; REPLICATION FACTOR C SUBUNIT 1; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF08519; RFC1; 1.
DR PIRSF; PIRSF036578; RFC1; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR036578};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR036578};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR036578}; Nucleus {ECO:0000256|PIRNR:PIRNR036578};
KW Reference proteome {ECO:0000313|Proteomes:UP000219813}.
FT DOMAIN 261..350
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 100..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 203..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 353..424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 941..994
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..32
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..380
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 381..402
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..420
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 959..978
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 994 AA; 113976 MW; A82BF61279AD9742 CRC64;
MCSKGKNLFD KDSDDDIGRK RKRLKKVSSN LFDNEEDDDD DFFDNEGKDK SLSKSVVEIN
DDDEVEEGNK NILEKKSLNK KASNKPVYYD ITSYFKPSSK KIDVNSNNNS NNNNNNNSNN
SNSNNSNSNN SNRNNSNSNN SNSNNRNSNN RNSNNSNSNN RNNNYSSNRN NSVMIKSSSN
NSSKIPVKNV SEYFDLLEKD QKNVKGENAK PNLKRERGQE GEQDVDIIEE ERYKKKLTSF
GKNKTKMENN DTTQKFDYLP FNNLKFVLTG VFKNFSRDDL QSKIKEHGGS VMSAVSSKTH
YLIHGEYLED GRLYNEGRKY LKAFELQQKS NSIIKILNEE QLLELLPEGK SHPQYEEQYG
THNGDANKEN SDKSEYQDFV KKQQSDYSTN YKSASDNYSS SNMLDKESRK DKHDNGLGNY
NNEVDERNKL SNNKVLNQLW VEKYRPKNIN ELVGNNQNVL KLKNWLASWE DVCIRGMKKQ
VTKTFRGIYE NVNARCALLS GAAGIGKTTT AKIISEASGY NVIEFNASDE RNKAAIEKIS
EMATGGYSIA SLKSRKLSKT CIIMDEVDGM SSGDKGGSAA ILKLIEKTKC PIICICNDRQ
NSKMRTLANK CYDLKFTVPN KNAVVKRLLE ICKKENIMME PNALELLWET TVGDMRQMLN
TLQLLSKTYK RIQFLDLKKE LNNSNKNVQS LANPFEITLK LLNFHESSKL KVREIMDLFF
VDYELIPYFI SENYTNVFND NDKSPNSINK WNAFAQISYD LALADKIKYN MKTTMDFSLL
PHFSILSCVC PVMRIKLLKL FMSGRINFPS AFGKISTFNK NKRLLNELCF NISYKLNVCP
KYMVTSGFLS YIYFKIMTPL LKNNINEAIE LMEEYNITRE MITEILPSLR LPNQENLYDK
LDSKVKASFT RLYNSSHVIK NDPNSLRKGL TSTEKKSTFK INEYESDEDM DELSESKEDK
DDDILVKSKI DRKPTIKNRS AAKPKAPSKN IKKR
//
