ID   A0A1D3L3V2_9EURY        Unreviewed;       187 AA.
AC   A0A1D3L3V2;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=dTMP kinase {ECO:0000256|ARBA:ARBA00029962};
GN   Name=tmk1 {ECO:0000313|EMBL:SCG86301.1};
GN   ORFNames=MCBB_1746 {ECO:0000313|EMBL:SCG86301.1};
OS   Methanobacterium congolense.
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanobacterium.
OX   NCBI_TaxID=118062 {ECO:0000313|EMBL:SCG86301.1, ECO:0000313|Proteomes:UP000094707};
RN   [1] {ECO:0000313|EMBL:SCG86301.1, ECO:0000313|Proteomes:UP000094707}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Buetzberg {ECO:0000313|EMBL:SCG86301.1};
RA   Seilhamer J.J.;
RL   Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + dTMP = ADP + dTDP; Xref=Rhea:RHEA:13517,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58369, ChEBI:CHEBI:63528,
CC         ChEBI:CHEBI:456216; EC=2.7.4.9;
CC         Evidence={ECO:0000256|ARBA:ARBA00001008};
CC   -!- SIMILARITY: Belongs to the thymidylate kinase family.
CC       {ECO:0000256|ARBA:ARBA00009776}.
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DR   EMBL; LT607756; SCG86301.1; -; Genomic_DNA.
DR   RefSeq; WP_071907377.1; NZ_LT607756.1.
DR   AlphaFoldDB; A0A1D3L3V2; -.
DR   STRING; 118062.MCBB_1746; -.
DR   GeneID; 30412584; -.
DR   KEGG; mcub:MCBB_1746; -.
DR   OrthoDB; 43083at2157; -.
DR   Proteomes; UP000094707; Chromosome I.
DR   GO; GO:0004798; F:thymidylate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR039430; Thymidylate_kin-like_dom.
DR   PANTHER; PTHR10344; THYMIDYLATE KINASE; 1.
DR   PANTHER; PTHR10344:SF4; THYMIDYLATE KINASE; 1.
DR   Pfam; PF02223; Thymidylate_kin; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000313|EMBL:SCG86301.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000094707};
KW   Transferase {ECO:0000313|EMBL:SCG86301.1}.
FT   DOMAIN          6..178
FT                   /note="Thymidylate kinase-like"
FT                   /evidence="ECO:0000259|Pfam:PF02223"
SQ   SEQUENCE   187 AA;  21475 MW;  C3CE12E0D60855F4 CRC64;
     MRFIVVDGLD GSGKTTHAEL IQRKYLEKGK KVVLRSHPSD DTKYGQKAKK ALLGRGKWNK
     TKATIYYAMD VIKSVRTGYG GVETLIFVRY LMGVAYLPLP LAKILYWVLT AFLPTSDYMF
     FLDLTPEESL HRMEDRDAEE MFENLEDLMK VRRKALSLTN GWHVIDTSGT IEEVHEKINR
     VLEGLED
//