ID   A0A1D3TZ01_9FIRM        Unreviewed;       413 AA.
AC   A0A1D3TZ01;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Site-specific recombinase XerD {ECO:0000313|EMBL:SCP99749.1};
GN   ORFNames=SAMN05421730_105618 {ECO:0000313|EMBL:SCP99749.1};
OS   Anaerobium acetethylicum.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Anaerobium.
OX   NCBI_TaxID=1619234 {ECO:0000313|EMBL:SCP99749.1, ECO:0000313|Proteomes:UP000199315};
RN   [1] {ECO:0000313|EMBL:SCP99749.1, ECO:0000313|Proteomes:UP000199315}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GluBS11 {ECO:0000313|EMBL:SCP99749.1,
RC   ECO:0000313|Proteomes:UP000199315};
RA   Capua I., De Benedictis P., Joannis T., Lombin L.H., Cattoli G.;
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Site-specific tyrosine recombinase, which acts by catalyzing
CC       the cutting and rejoining of the recombining DNA molecules.
CC       {ECO:0000256|ARBA:ARBA00003283}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC       {ECO:0000256|ARBA:ARBA00008857}.
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DR   EMBL; FMKA01000056; SCP99749.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1D3TZ01; -.
DR   STRING; 1619234.SAMN05421730_105618; -.
DR   OrthoDB; 9803188at2; -.
DR   Proteomes; UP000199315; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008907; F:integrase activity; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR   CDD; cd01189; INT_ICEBs1_C_like; 1.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR   Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR   InterPro; IPR044068; CB.
DR   InterPro; IPR016177; DNA-bd_dom_sf.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   InterPro; IPR004107; Integrase_SAM-like_N.
DR   InterPro; IPR004191; Integrase_Tn916-type_DNA-bd_N.
DR   PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR   PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR   Pfam; PF02920; Integrase_DNA; 1.
DR   Pfam; PF14659; Phage_int_SAM_3; 1.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR   SUPFAM; SSF54171; DNA-binding domain; 1.
DR   PROSITE; PS51900; CB; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU01248}; Reference proteome {ECO:0000313|Proteomes:UP000199315};
KW   Viral genome integration {ECO:0000256|ARBA:ARBA00023195};
KW   Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT   DOMAIN          72..154
FT                   /note="Core-binding (CB)"
FT                   /evidence="ECO:0000259|PROSITE:PS51900"
FT   DOMAIN          180..408
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000259|PROSITE:PS51898"
SQ   SEQUENCE   413 AA;  48201 MW;  55E88B8A7EEFDEF8 CRC64;
     MAARKDGKGR ALRKGESYRK SEGRTRYSYC YTDPFGKRKY IYSNNLATLR EREEQLIRNQ
     MDGLDVYVAG SATLNYVFDR YLSTKTELRS TTYSNYRYTW DHFIKDGFGK KKIGDVKYSD
     VLAFYNHLIT ELGLQVNTLE SINTVLHPTF QLAVRDDIIR KNPTDGAYAE IKKRNGGSRK
     TRHALTVEQQ RSFMQYVAKN PIFYVWYPFF MLLLGTGCRI GEAIGLRWDD VDMEKRLISI
     NHSLTYYPRR EETYVCEFRV SKPKTEAGVR TIPIMEQLYQ ILLQERERQK QEGFCSNEVD
     GMTNFIFTNR FGNPHNPAAV NRAIKRIVDA HNAEEEIKAK KQKREPVMLP RFSCHIFRHT
     FASRFCENET NVKVIQEVMG HADVSTTMNI YAEVNESITR QSLENLAKNM DVF
//