ID A0A1D5NWM8_CHICK Unreviewed; 324 AA.
AC A0A1D5NWM8;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Ras association domain family member 2 {ECO:0000313|Ensembl:ENSGALP00010026182.1};
GN Name=RASSF2 {ECO:0000313|Ensembl:ENSGALP00010026182.1};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010026182.1, ECO:0000313|Proteomes:UP000000539};
RN [1] {ECO:0000313|Ensembl:ENSGALP00010026182.1}
RP IDENTIFICATION.
RC STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010026182.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A1D5NWM8; -.
DR SMR; A0A1D5NWM8; -.
DR STRING; 9031.ENSGALP00000044768; -.
DR PaxDb; 9031-ENSGALP00000000272; -.
DR Ensembl; ENSGALT00010044037.1; ENSGALP00010026182.1; ENSGALG00010018233.1.
DR VEuPathDB; HostDB:geneid_419521; -.
DR GeneTree; ENSGT00940000158546; -.
DR InParanoid; A0A1D5NWM8; -.
DR OMA; DYGGCEY; -.
DR OrthoDB; 4211308at2759; -.
DR Proteomes; UP000000539; Chromosome 22.
DR Bgee; ENSGALG00000030432; Expressed in granulocyte and 11 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0000776; C:kinetochore; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR GO; GO:0004672; F:protein kinase activity; IEA:Ensembl.
DR GO; GO:0046849; P:bone remodeling; IEA:Ensembl.
DR GO; GO:0007249; P:canonical NF-kappaB signal transduction; IEA:Ensembl.
DR GO; GO:0048872; P:homeostasis of number of cells; IEA:Ensembl.
DR GO; GO:1901223; P:negative regulation of non-canonical NF-kappaB signal transduction; IEA:Ensembl.
DR GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR GO; GO:0001503; P:ossification; IEA:Ensembl.
DR GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR GO; GO:0046330; P:positive regulation of JNK cascade; IBA:GO_Central.
DR GO; GO:0031954; P:positive regulation of protein autophosphorylation; IEA:Ensembl.
DR GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
DR GO; GO:1901222; P:regulation of non-canonical NF-kappaB signal transduction; IBA:GO_Central.
DR GO; GO:0045667; P:regulation of osteoblast differentiation; IEA:Ensembl.
DR GO; GO:0045670; P:regulation of osteoclast differentiation; IEA:Ensembl.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR CDD; cd17221; RA_RASSF2; 1.
DR CDD; cd21893; SARAH_RASSF2; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR033614; RASSF1-6.
DR InterPro; IPR033618; RASSF2_RA.
DR InterPro; IPR011524; SARAH_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR22738:SF14; RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR22738; RASSF; 1.
DR Pfam; PF16517; Nore1-SARAH; 1.
DR Pfam; PF00788; RA; 1.
DR SMART; SM00314; RA; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50200; RA; 1.
DR PROSITE; PS50951; SARAH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000539}.
SQ SEQUENCE 324 AA; 37366 MW; 099B32022E82ED6D CRC64;
MEYGSCEYLV PCGKDKFISK NELLLHLKTY NIYYEGQNLQ LRHREEEGEL IVEGLLNISW
GLRRPIRLQM QDDNQRIRPP PSSSSWHSGC NLGAHGSVLK PSTLPDIQVT DVDAAVNTES
TGSNTGTTRL QPEDPPQLLR TRSDVGVRRR GSSRTPSEQR RIRRHRFSIN GHFYNHKTSV
FTPAYGSITN VRINSTMTTP QVLKLLLNKF KIENSAEEFA LYIVHTSGEK QKLRATDYPL
IARVLQGPCE QVSKVFLMEK DQVEEVTYDV AQYIKFEMPV LRSFIQKLEE EEDREVKKLM
RKYSILRLMI EQRLEEISEG PARL
//
