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Database: UniProt
Entry: A0A1D5P5B9_CHICK
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ID   A0A1D5P5B9_CHICK        Unreviewed;      1084 AA.
AC   A0A1D5P5B9;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 2.
DT   08-MAY-2019, entry version 17.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGALP00000047886};
GN   Name=NLRC3 {ECO:0000313|Ensembl:ENSGALP00000047886};
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
OC   Phasianidae; Phasianinae; Gallus.
OX   NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00000047886, ECO:0000313|Proteomes:UP000000539};
RN   [1] {ECO:0000313|Ensembl:ENSGALP00000047886, ECO:0000313|Proteomes:UP000000539}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000047886,
RC   ECO:0000313|Proteomes:UP000000539};
RX   PubMed=15592404; DOI=10.1038/nature03154;
RG   International Chicken Genome Sequencing Consortium;
RA   Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C.,
RA   Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E.,
RA   Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W.,
RA   Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A., Kremitzki C.,
RA   Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E.,
RA   Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J.,
RA   Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M.,
RA   Paton B., Smith J., Morrice D., Daniels L., Tempest H.G.,
RA   Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V.,
RA   Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J.,
RA   van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J.,
RA   Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H.,
RA   Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K.,
RA   Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E.,
RA   Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M.,
RA   Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S.,
RA   Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J.,
RA   Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H.,
RA   Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C.,
RA   Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C.,
RA   Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P.,
RA   King D.C., Yang S.-P., Tyekucheva S., Radakrishnan A., Harris R.S.,
RA   Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S.,
RA   Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S.,
RA   Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z.,
RA   Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J.,
RA   Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z.,
RA   Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M.,
RA   Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O.,
RA   Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J.,
RA   Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G.,
RA   Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D.,
RA   Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G.,
RA   Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A.,
RA   Mardis E.R., Wilson R.K.;
RT   "Sequence and comparative analysis of the chicken genome provide
RT   unique perspectives on vertebrate evolution.";
RL   Nature 432:695-716(2004).
RN   [2] {ECO:0000313|Ensembl:ENSGALP00000047886}
RP   IDENTIFICATION.
RC   STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000047886};
RG   Ensembl;
RL   Submitted (OCT-2016) to UniProtKB.
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DR   EMBL; AADN05000376; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSGALT00000076783; ENSGALP00000047886; ENSGALG00000033278.
DR   GeneTree; ENSGT00940000159861; -.
DR   OrthoDB; 259987at2759; -.
DR   Proteomes; UP000000539; Chromosome 14.
DR   ExpressionAtlas; A0A1D5P5B9; baseline and differential.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   Gene3D; 3.80.10.10; -; 3.
DR   InterPro; IPR001315; CARD.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRC_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   Pfam; PF00619; CARD; 1.
DR   Pfam; PF13516; LRR_6; 11.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SMART; SM01288; FISNA; 1.
DR   SUPFAM; SSF47986; SSF47986; 1.
DR   PROSITE; PS50209; CARD; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|SAAS:SAAS01046498};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000539};
KW   Leucine-rich repeat {ECO:0000256|SAAS:SAAS01143294};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS01046502};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000539};
KW   Repeat {ECO:0000256|SAAS:SAAS01046485}.
FT   DOMAIN       36    120       CARD. {ECO:0000259|PROSITE:PS50209}.
FT   DOMAIN      198    330       NACHT. {ECO:0000259|PROSITE:PS50837}.
SQ   SEQUENCE   1084 AA;  119136 MW;  0C33FDC79A63E5C4 CRC64;
     MGWWWVQAEV CTAVNTVLIA PGRRCHGTPL MEEAWISRYR RQLMRSISPQ FLEEIIGYLQ
     RLDLLTVEEA GRAQEASSLP EQVRAVVDIL AGKGSHASQT LQSFIETTNS QLYLHITVYE
     PMVQKHLESL QSFYGNSLEI GSLQRLTNLL LVEGLTDIQQ KEHDILQMEM TKGLRNVSKS
     IPLEKLFLPL SKVSIPPRIS VTTGVAGIGK STLVKLFVGR WTKGLINRDI MFVLPLTFRE
     LNTYEKLSAE RLIRSSFPHI TEPNCISTGA ARTLLILDGL DEFKTPLDFS NTVACTDPKK
     EIQVDNLITN IIRGNLLQEA SIWVTSRPTA ASQIPGGLVD RMTEIRGFRA TEMKDFLDQM
     FLDNKDLSGQ VLHHIKANRS LHIMCTVPGF CRIYGSSIGY YLKNSTGQPQ EMTVAPKTLS
     EIYSYYFKMA LSSDWPERQR ETLRIEQAVN NSKKVMGSLG RLAFYGLLKR KHVFYEQDMK
     AYGIDLSLLH SSLCSRLLLK EDMQSTTAYY FSHLTIQEFL AAIYYYTAAK RAIFDLFTES
     GMSWPKLGFL NHFKSAVQRS LQAEDGQLDI FVRFLSGLLS PQTVNTVHCL HEIQHTEIAK
     AVEEAMKNES LAGMLTPVNC SALAYLLQVS DVCVEETNLS NCLTYNICKS LLPQLLFCHS
     LRLDNNQFKD NVMELLGSML SVKDCQIQRL SLAENQICNK GAKALARSLM VNRSLTVLDL
     RSNSIGPSGA KALADALKKN QVLLSLSLQH NVIKEEGAAA LAEALLTNRR LITLHLQKNS
     IGAHGARKLA EALAQNCSLK ELMLSSNSVG DNGSVALAEA LKVNHSLQSL DLQSNSISNT
     GVSALTAALC SNKGLTDLNL RENSISKEGG PAIAHALRTN CTLRKLDLAA NLLHDEGGKA
     IALAMKENRA LTSLHLQWNF IQTQAAVALA QALQSNDSLA SLDLQENAIG DEGMAALAAA
     LKVNTTLADL HLQVASISAA GAQALAEALM VNNSLQVLDL RGNSISVAGA KAMANALKVN
     RSLRWLNLQE NSLGMDGAIC IATALRGNHG LTYVNLQGNR IGQSGAKMIS DAIRTNSPDC
     VVVV
//
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