ID   A0A1D5PI24_CHICK        Unreviewed;       732 AA.
AC   A0A1D5PI24;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 2.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=Nuclear factor of activated T cells 1 {ECO:0000313|Ensembl:ENSGALP00010009587.1};
GN   Name=NFATC1 {ECO:0000313|Ensembl:ENSGALP00010009587.1};
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010009587.1, ECO:0000313|Proteomes:UP000000539};
RN   [1] {ECO:0000313|Ensembl:ENSGALP00010009587.1}
RP   IDENTIFICATION.
RC   STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010009587.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_015131427.1; XM_015275941.1.
DR   AlphaFoldDB; A0A1D5PI24; -.
DR   Ensembl; ENSGALT00010017306.1; ENSGALP00010009587.1; ENSGALG00010007252.1.
DR   GeneID; 420815; -.
DR   CTD; 4772; -.
DR   VEuPathDB; HostDB:geneid_420815; -.
DR   GeneTree; ENSGT00940000157616; -.
DR   Proteomes; UP000000539; Chromosome 2.
DR   Bgee; ENSGALG00000042534; Expressed in muscle tissue and 12 other cell types or tissues.
DR   ExpressionAtlas; A0A1D5PI24; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR   GO; GO:0043227; C:membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0048699; P:generation of neurons; NAS:ParkinsonsUK-UCL.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IMP:ParkinsonsUK-UCL.
DR   CDD; cd07881; RHD-n_NFAT; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.60.40.340; Rel homology domain (RHD), DNA-binding domain; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002909; IPT_dom.
DR   InterPro; IPR008366; NFAT.
DR   InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR   InterPro; IPR032397; RHD_dimer.
DR   InterPro; IPR011539; RHD_DNA_bind_dom.
DR   InterPro; IPR037059; RHD_DNA_bind_dom_sf.
DR   PANTHER; PTHR12533; NFAT; 1.
DR   PANTHER; PTHR12533:SF5; NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 1; 1.
DR   Pfam; PF16179; RHD_dimer; 1.
DR   Pfam; PF00554; RHD_DNA_bind; 1.
DR   PRINTS; PR01789; NUCFACTORATC.
DR   SMART; SM00429; IPT; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   SUPFAM; SSF49417; p53-like transcription factors; 1.
DR   PROSITE; PS50254; REL_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000539}.
SQ   SEQUENCE   732 AA;  80135 MW;  E0C712A8E683CEBB CRC64;
     MPSAAPPAAA AAPPSRDPAA TGRERPPAAP QHGARLLGST MKAAEEEHYN YTSSNVNAGL
     PLNVAHSSLS TPCHGLQTSN PIISVVPSTN HPSGYGGHID SGASEYYLPP NIRPNGAPAL
     ESPRIEITSY MGLHHNNNQF FHDEVEEAIP NAKRSPSTAT LNLPNLEAYR DPSCLSPASS
     LSSRSCNSEA SSYESNYSYP YTSPQTSPWQ SPCVSPKTTD TEEGYQRGMV ACTLLSSPRH
     SPSTSPRTSV TEENWLGARG SRPPSPCNKR KYSLNGRQTS YSPHHSPTPS PQNSPRVSVT
     DETWLGNTNQ YTSSAIVAAI NALTTDSTID MNDGIPIKSR KTAIDHTPSM TLKTEPAGED
     HGNISPTADL SPEDFSSFQH IRKGNFCEQY LSVPQHPYQW AKPKSLSPTS YMSPSLPALD
     WQLPSHSGPY ELRIEVQPKS HHRAHYETEG SRGAVKASAG GHPIVQLHGY LESEPLTLQL
     FIGTADDRLL RPHAFYQVHR ITGKTVSTTS HETILSNTKV LEIPLLPENN MRATIDCAGI
     LKLRNSDIEL RKGETDIGRK NTRVRLVFRV HIPQSNGRTL SLQVASNPIE CSQRSAQELP
     LVEKQSTDSF PVTGGKKMIL TGHNFLQDSK VIFLEKAPDG HHVWEMEAKT DKEMCKPNSL
     VVEIPPFRNQ RITSPVQVNF YVCNGKRKRS QYQIFTYLPA NGENSQWTQG HVTSLILPPV
     DGPGVSPWST AL
//