ID A0A1D5PIE4_CHICK Unreviewed; 450 AA.
AC A0A1D5PIE4;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Antizyme inhibitor 1 {ECO:0000313|Ensembl:ENSGALP00010016652.1};
GN Name=AZIN1 {ECO:0000313|Ensembl:ENSGALP00010016652.1};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010016652.1, ECO:0000313|Proteomes:UP000000539};
RN [1] {ECO:0000313|Ensembl:ENSGALP00010016652.1}
RP IDENTIFICATION.
RC STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010016652.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-II family.
CC {ECO:0000256|RuleBase:RU003737}.
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DR RefSeq; NP_001008729.1; NM_001008729.2.
DR AlphaFoldDB; A0A1D5PIE4; -.
DR SMR; A0A1D5PIE4; -.
DR STRING; 9031.ENSGALP00000052577; -.
DR PaxDb; 9031-ENSGALP00000035817; -.
DR Ensembl; ENSGALT00010028893.1; ENSGALP00010016652.1; ENSGALG00010012061.1.
DR GeneID; 420254; -.
DR KEGG; gga:420254; -.
DR CTD; 51582; -.
DR VEuPathDB; HostDB:geneid_420254; -.
DR GeneTree; ENSGT00950000182995; -.
DR InParanoid; A0A1D5PIE4; -.
DR OMA; FNGLYEM; -.
DR OrthoDB; 48358at2759; -.
DR Reactome; R-GGA-350562; Regulation of ornithine decarboxylase (ODC).
DR Proteomes; UP000000539; Chromosome 2.
DR Bgee; ENSGALG00000029295; Expressed in spermatid and 13 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0042978; F:ornithine decarboxylase activator activity; IBA:GO_Central.
DR GO; GO:0004586; F:ornithine decarboxylase activity; IBA:GO_Central.
DR GO; GO:0042177; P:negative regulation of protein catabolic process; IBA:GO_Central.
DR GO; GO:1902269; P:positive regulation of polyamine transmembrane transport; IBA:GO_Central.
DR GO; GO:0033387; P:putrescine biosynthetic process from ornithine; IBA:GO_Central.
DR CDD; cd06831; PLPDE_III_ODC_like_AZI; 1.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR InterPro; IPR031178; Azin1.
DR InterPro; IPR022643; De-COase2_C.
DR InterPro; IPR022657; De-COase2_CS.
DR InterPro; IPR022644; De-COase2_N.
DR InterPro; IPR000183; Orn/DAP/Arg_de-COase.
DR InterPro; IPR002433; Orn_de-COase.
DR InterPro; IPR029066; PLP-binding_barrel.
DR PANTHER; PTHR11482:SF7; ANTIZYME INHIBITOR 1; 1.
DR PANTHER; PTHR11482; ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE; 1.
DR Pfam; PF02784; Orn_Arg_deC_N; 1.
DR Pfam; PF00278; Orn_DAP_Arg_deC; 1.
DR PRINTS; PR01179; ODADCRBXLASE.
DR PRINTS; PR01182; ORNDCRBXLASE.
DR SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
DR PROSITE; PS00879; ODR_DC_2_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000539}.
FT DOMAIN 46..278
FT /note="Orn/DAP/Arg decarboxylase 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02784"
FT DOMAIN 279..387
FT /note="Orn/DAP/Arg decarboxylase 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00278"
SQ SEQUENCE 450 AA; 50010 MW; 25259E96366B4A15 CRC64;
MKGFLEDANY SIGLLDEGAT LADVIDNCIY EHTHTGKRAF YVGDLGKLVK KNIQWQNVMA
PIKPFYTVRC NSTPGVLEIL GTLGIGFACS SKSEMALVQG LGISPENIIY TNPCKQASQI
KYAAKAGINI MTCDSDIELK KIARNHPNAK LLLHIATEDI TADEEMNMKF GTTLKNCRHL
MECAKEFGVQ IVGVKFHVSG SCKELQTYIH AISDARCVFD MAEEFGFKMN MLDIGGGFTG
SELQLEEVNH VIRPLLDVYF PKESGIQVIA EPGCYYVSSA FTLAVNVIAK KAVDCDKLLP
SGVEQARNDD EPVFTYYIND GVYGSFASKL SEKLYTNPEV HKKYKEDEPL FASSLWGPSC
DELDQIVENC LLPELSVGDW LIFDNMGSGT LGEQSTFNDY QRPLIYYMMS FSDWDEMQDA
GIASDTLMKN FFFVPSCIQL SPEDRFSTAA
//
