ID   A0A1D5PRM4_CHICK        Unreviewed;      1437 AA.
AC   A0A1D5PRM4;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Strawberry notch homolog 2 {ECO:0000313|Ensembl:ENSGALP00010041618.1};
GN   Name=SBNO2 {ECO:0000313|Ensembl:ENSGALP00010041618.1};
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010041618.1, ECO:0000313|Proteomes:UP000000539};
RN   [1] {ECO:0000313|Ensembl:ENSGALP00010041618.1}
RP   IDENTIFICATION.
RC   STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010041618.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the SBNO family.
CC       {ECO:0000256|ARBA:ARBA00006992}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_015155465.1; XM_015299979.1.
DR   STRING; 9031.ENSGALP00000055551; -.
DR   Ensembl; ENSGALT00010067875.1; ENSGALP00010041618.1; ENSGALG00010028001.1.
DR   GeneID; 420104; -.
DR   CTD; 22904; -.
DR   VEuPathDB; HostDB:geneid_420104; -.
DR   GeneTree; ENSGT00940000159946; -.
DR   InParanoid; A0A1D5PRM4; -.
DR   OMA; ARHSHKR; -.
DR   OrthoDB; 3541637at2759; -.
DR   Proteomes; UP000000539; Chromosome 28.
DR   Bgee; ENSGALG00000037522; Expressed in granulocyte and 12 other cell types or tissues.
DR   ExpressionAtlas; A0A1D5PRM4; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0031490; F:chromatin DNA binding; IBA:GO_Central.
DR   GO; GO:0042393; F:histone binding; IBA:GO_Central.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0061430; P:bone trabecula morphogenesis; IEA:Ensembl.
DR   GO; GO:0071348; P:cellular response to interleukin-11; IEA:Ensembl.
DR   GO; GO:0071354; P:cellular response to interleukin-6; IBA:GO_Central.
DR   GO; GO:1990830; P:cellular response to leukemia inhibitory factor; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0002281; P:macrophage activation involved in immune response; IBA:GO_Central.
DR   GO; GO:0045892; P:negative regulation of DNA-templated transcription; IBA:GO_Central.
DR   GO; GO:0030316; P:osteoclast differentiation; IBA:GO_Central.
DR   GO; GO:0072675; P:osteoclast fusion; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   GO; GO:0050727; P:regulation of inflammatory response; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR026937; SBNO_Helicase_C_dom.
DR   InterPro; IPR026741; SNO.
DR   InterPro; IPR039187; SNO_AAA.
DR   PANTHER; PTHR12706:SF5; PROTEIN STRAWBERRY NOTCH HOMOLOG 2; 1.
DR   PANTHER; PTHR12706; STRAWBERRY NOTCH-RELATED; 1.
DR   Pfam; PF13872; AAA_34; 1.
DR   Pfam; PF13871; Helicase_C_4; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000539}.
FT   DOMAIN          234..527
FT                   /note="Strawberry notch AAA"
FT                   /evidence="ECO:0000259|Pfam:PF13872"
FT   DOMAIN          759..1037
FT                   /note="Strawberry notch helicase C"
FT                   /evidence="ECO:0000259|Pfam:PF13871"
SQ   SEQUENCE   1437 AA;  161744 MW;  82379B5FA0500997 CRC64;
     MPSAHVAMDG GKSCPQHEQQ PAADALCSIP GFCSPLAVPP MESSMLAADS WSDCYPAPFP
     TSSFPSENQQ YFNSSHDFYM NPISRPHFLD TNYASVDPTD FLPKNGDFPQ DSSYLDELSN
     NNSLFSSPAD SLSDIVDAKD CLPADSLNHV PTIWDVNTSQ QNQTELFSPS RSFSGLNSSD
     DRIPAVPNTP LLISYQSQAP AEEEDEGDEE ETEELGQTET YAEYIPSKSK IGKHHPDLVV
     ETSTLSSVPP PDITYSLSLP SSVADKGSLS ALQLEAIIYA CQQHEVLLPN GQRAGFLIGD
     GAGVGKGRTV AGIIFENYLK GRKKALWFSV SNDLKYDAER DLKDIEASHI PVHALNKIRY
     GDTATSEGVL FATYSALIGE SQAGGQHRTR LKQILDWCRE NFDGVIVFDE CHKAKNASST
     KMGKAVLDLQ NKLPQARVVY ASATGASEPK NMIYMSRLGI WGEGTPFRAF DEFLHAIEKR
     GVGAMEIVAM DMKVSGMYIA RQLSFTGVTF RIEEIPLDQQ YKIVYDKAAK LWAEALMVFQ
     QAADLIGLES RKSLWGQFWS AHQRFFKYLC IAAKVRRLVE LAKEELAKDK CIVIGLQSTG
     EARTREVLDE NDGHLNCFVS AAEGVFLSLI QKHFPSTKRK REKGTGIKRK RKQRGRCAKT
     LKGMCDPVGV IKISDDSSTD SDMGLDSDFN SSPESVLEND DVIFIEHAFN GFVTESRSNF
     HMLPSHKEMH GLRELEHVEK MKQDLLAKVK ALGKELPLNT LDELINHFGG PEHVAEMTGR
     KGRVVCRPDG SVMFESRAEQ GLSIDHVNLK EKERFMNGEK LVAIISEASS SGISLQADRR
     VKNQKRRVHM TLELPWSADR AIQQFGRTHR SNQVSAPEYV FLISELAGER RFASIVAKRL
     ESLGALTHGD RRATESRDLS KYNFENKYGA KALDRVLSTI LNYKENRVPV PKSYERGEAA
     FFQEMKQGLI SVGICCNQLK YGTVSVEKDC SITKFLNRIL GLEVDKQNML FQYFSDTFDY
     LIEKDKKEGK YDMGILDLAP GIDEIYEESK EVFLTPGHPQ DGQVVFYKIS VDRGLKWEEA
     YEKSLKLTGS YDGFYLSYKT RGNKYTCLLA EQGRGKNFIL YKPNIGKQSQ PESLDSLHKK
     YRQVTPEEAK EHWESCYHFS LKKCNHAVWN RSCKLIQEGK ECFQGMRLRH YYMLCGALLR
     VWSRIASIMA DITNTSYLQI VRLKTKEKKK QVGIKIPESC VRKVLEELKQ MDENVKRKHN
     RLLQAQEQSL QFPLSLHMLQ QPLDLTQTAP GLPLPQHSLR QDEILDLTYS PPSDSIPDMM
     NPEPSTLCFP PEPVLQPHQQ HGSPFGFSHL PAFKSPDTIL EGSVPLSSSL QEHQPLPHPE
     PSQTLQQQED FVQQDGNINF REILEDMLRT FNGAPQENIL PQERQSVIQF WKSPLNF
//