ID A0A1D5QDW9_MACMU Unreviewed; 464 AA.
AC A0A1D5QDW9;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=FERM domain-containing protein 8 {ECO:0000256|ARBA:ARBA00039547};
GN Name=FRMD8 {ECO:0000313|EMBL:AFH34243.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:AFH34243.1};
RN [1] {ECO:0000313|EMBL:AFH34243.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Orbital {ECO:0000313|EMBL:AFJ71741.1}, Testis
RC {ECO:0000313|EMBL:AFI33776.1}, and Thymus
RC {ECO:0000313|EMBL:AFH34243.1};
RX PubMed=25319552; DOI=10.1186/1745-6150-9-20;
RA Zimin A.V., Cornish A.S., Maudhoo M.D., Gibbs R.M., Zhang X., Pandey S.,
RA Meehan D.T., Wipfler K., Bosinger S.E., Johnson Z.P., Tharp G.K.,
RA Marcais G., Roberts M., Ferguson B., Fox H.S., Treangen T., Salzberg S.L.,
RA Yorke J.A., Norgren R.B.Jr.;
RT "A new rhesus macaque assembly and annotation for next-generation
RT sequencing analyses.";
RL Biol. Direct 9:20-20(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
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DR EMBL; JU477439; AFH34243.1; -; mRNA.
DR EMBL; JV043705; AFI33776.1; -; mRNA.
DR EMBL; JV636401; AFJ71741.1; -; mRNA.
DR RefSeq; NP_001247833.1; NM_001260904.1.
DR AlphaFoldDB; A0A1D5QDW9; -.
DR GeneID; 716379; -.
DR KEGG; mcc:716379; -.
DR CTD; 83786; -.
DR eggNOG; KOG4335; Eukaryota.
DR OrthoDB; 2879691at2759; -.
DR TreeFam; TF317921; -.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR13283:SF10; FERM DOMAIN-CONTAINING PROTEIN 8; 1.
DR PANTHER; PTHR13283; KREV INTERACTION TRAPPED 1-RELATED; 1.
DR Pfam; PF00373; FERM_M; 1.
DR SMART; SM00295; B41; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 2: Evidence at transcript level;
FT DOMAIN 30..376
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 376..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 464 AA; 51252 MW; D3CE582DF5E35B91 CRC64;
MDGTEGSTGQ PGPAERSHRS SVSSVGARAA DVLVYLADDT VVPLAVENLP SLSAHELHRA
VREVLQLPDI ALDVFALWLV SPLLEVQLKP KHQPYKLGRQ WPELLLRFTS APDDDVAMDE
PFLQFRRNVF FPKRRELQIR DEEVLRLLYE EAKGNVLAAR YPCDVEDCEA LGALVCRVQL
GPYQPGQPAA CALREKLDSF LPAHLCKRGQ GLFAALRGRG TRAGPGEQGL LNAYRQVQEV
GSDGGCEAAL GTHYRAYLFK CHELPFYGCA FFHGEVDKPA QGFLHRGGRK PVSVAISLEG
VHVIDSREKH VLLGLRFQEL SWDHTSPEEE EPILWLEFDG DSEGTPVNKL LKIYSKQAEL
MSSLIEYCIE LSQVAEPAGP QDSATGPPSD PSSSPAPVER PKLRRQGSVV SSRIQHLSTI
DYVEDGKGIR RVKPKRTTSF FSRQLSLGQG SYTVVQPSDS LEQG
//
