ID A0A1D5QHS6_MACMU Unreviewed; 672 AA.
AC A0A1D5QHS6;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Rubicon like autophagy enhancer {ECO:0000313|Ensembl:ENSMMUP00000047598.2};
GN Name=RUBCNL {ECO:0000313|Ensembl:ENSMMUP00000047598.2,
GN ECO:0000313|VGNC:VGNC:77063};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000047598.2, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000047598.2}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000047598.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A1D5QHS6; -.
DR Ensembl; ENSMMUT00000072680.2; ENSMMUP00000047598.2; ENSMMUG00000009862.4.
DR VEuPathDB; HostDB:ENSMMUG00000009862; -.
DR VGNC; VGNC:77063; RUBCNL.
DR GeneTree; ENSGT00940000160585; -.
DR Proteomes; UP000006718; Chromosome 17.
DR Bgee; ENSMMUG00000009862; Expressed in ileum and 23 other cell types or tissues.
DR ExpressionAtlas; A0A1D5QHS6; baseline.
DR InterPro; IPR025258; RH_dom.
DR InterPro; IPR048569; RUBC_PIKBD.
DR PANTHER; PTHR45971; PHOX (PX) DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45971:SF2; PROTEIN ASSOCIATED WITH UVRAG AS AUTOPHAGY ENHANCER; 1.
DR Pfam; PF13901; RH_dom; 1.
DR Pfam; PF21054; RUBC_PIKBD; 1.
DR SMART; SM01175; DUF4206; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006718}.
FT DOMAIN 451..663
FT /note="Rubicon Homology"
FT /evidence="ECO:0000259|SMART:SM01175"
FT REGION 72..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 672 AA; 74574 MW; 2E26DC64E16804E0 CRC64;
MVSQSTVRQD SPEDPWERIT HYSGIIDGPP GLLNTDHPPC QLDIRLMRHK AAWINPQDVQ
QQLQDLQPQV PAAGNSGTHF VTDAASPSGP SSSCLRDSLA ETTLSEATTD SIGSASPHGS
REKSSSFSLS STEGHMVHPG YSHQVSLPTS PRILVTSPYP ETDSAFFEPS HLTSAAAEDA
VQVSRRTISL NSFSPEVFVL PVDVEKENAH FHVADMIISA MEKMKCNILS QQQTENWSKE
EASGLLGSDQ PDSDVTFDTN IKQESGSSTS SYSGYEGCAV LQVSPVTETR PYPDVKEICQ
CDIDEFVILE LGDFNDITET CSCSCNSSKS VTYEPEFNSA ELLAKELYRV FRKCWMLSLV
NSQLAGSLSA AGSIVVNEER VRKNFESSMN VVQEIKFKSR IRGTEDWAPP RFQIIFNIHP
PLKRDLVVAA QNFFCAGCGT PIEPKFVKRL RYCEYLGKYF CDCCHSYAES CIPARILMMW
DFKKYYVSNF SKRLLDSIWN QPIFNLLSIG QSLYAKAKEL GRMKEIQEQL FHIKKLLKTC
RFADSALKEF EQVPGHLTDE LHLFSLEDLV RIKKGLLAPL LKDILKASLA HVAGCELCQG
KGFICEFCQN TTVIFPFQTA TCRRCSGSVA GLAPQQGDSG AEICQKKFHV PQLNTCGGVQ
AARLGEGEVE QW
//
