ID A0A1D5QJ99_MACMU Unreviewed; 401 AA.
AC A0A1D5QJ99;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=HSF-type DNA-binding domain-containing protein {ECO:0000259|SMART:SM00415};
GN Name=LOC106995433 {ECO:0000313|Ensembl:ENSMMUP00000048122.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000048122.1, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Ensembl:ENSMMUP00000048122.1}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000048122.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HSF family. {ECO:0000256|ARBA:ARBA00006403,
CC ECO:0000256|RuleBase:RU004020}.
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DR RefSeq; XP_014984149.1; XM_015128663.1.
DR AlphaFoldDB; A0A1D5QJ99; -.
DR SMR; A0A1D5QJ99; -.
DR STRING; 9544.ENSMMUP00000048122; -.
DR Ensembl; ENSMMUT00000059031.2; ENSMMUP00000048122.1; ENSMMUG00000049379.1.
DR GeneID; 106995433; -.
DR KEGG; mcc:106995433; -.
DR VEuPathDB; HostDB:ENSMMUG00000049379; -.
DR GeneTree; ENSGT00940000157452; -.
DR InParanoid; A0A1D5QJ99; -.
DR OMA; HCPNCNC; -.
DR OrthoDB; 5358111at2759; -.
DR Proteomes; UP000006718; Unassembled WGS sequence.
DR Bgee; ENSMMUG00000049379; Expressed in spermatid and 3 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000232; HSF_DNA-bd.
DR InterPro; IPR027725; HSF_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10015; HEAT SHOCK TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR10015:SF336; HEAT SHOCK TRANSCRIPTION FACTOR, Y-LINKED; 1.
DR Pfam; PF00447; HSF_DNA-bind; 1.
DR SMART; SM00415; HSF; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000006718}.
FT DOMAIN 76..194
FT /note="HSF-type DNA-binding"
FT /evidence="ECO:0000259|SMART:SM00415"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 260..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 380..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 401 AA; 45769 MW; B1E686185F2A4CE3 CRC64;
MEHVSSETQD VSPEDELTDS EASNRSPLCE HTFPEDSDLR SMIEENAFQV LSQGSSLKRP
RYTACDSEPD KDNGFFSLTF PRKLWKIVES DQFKSISWDE NGTCIMINEE LFKKEILERK
APYRIFQTDS IKSFIRQLNL YGFSKIQQNF QRSAFVATFL AEEKESFVLS KLKFYYNPHF
KRGCPQLLVR VKRRIGVKNT SLISTLFNED FNRKHFRAGA NMDNHNSALA AKASEESLFS
TSKNLNMPLT RESSVRQMTA NSSGPIRSGF PHPSPSTSVG PSDEIATNQH SILNQLTTIH
MHSYSTYMQA RGHIVNFITT TTSHYHIISP LQNRYLRLLV EPSAIPRRCH VVSVNEAPYP
NLLPAGNPWL QMPVRADTLT APRSRPALQP SLLDKYHPNY N
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