ID A0A1D5QLD6_MACMU Unreviewed; 1302 AA.
AC A0A1D5QLD6;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000048861.2};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000048861.2, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000048861.2}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000048861.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May play a role in spermatogenesis.
CC {ECO:0000256|ARBA:ARBA00037695}.
CC -!- SIMILARITY: Belongs to the SPATA31 family.
CC {ECO:0000256|ARBA:ARBA00035009}.
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DR Ensembl; ENSMMUT00000060454.2; ENSMMUP00000048861.2; ENSMMUG00000038652.2.
DR VEuPathDB; HostDB:ENSMMUG00000038652; -.
DR eggNOG; ENOG502RU0E; Eukaryota.
DR GeneTree; ENSGT00950000183043; -.
DR InParanoid; A0A1D5QLD6; -.
DR OMA; SHTPWSA; -.
DR Proteomes; UP000006718; Chromosome 15.
DR Bgee; ENSMMUG00000038652; Expressed in spermatid and 3 other cell types or tissues.
DR ExpressionAtlas; A0A1D5QLD6; baseline.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR039509; SPATA31.
DR InterPro; IPR027970; SPATA31F3-like.
DR PANTHER; PTHR21859; ACROSOME-SPECIFIC PROTEIN; 1.
DR PANTHER; PTHR21859:SF55; SPERMATOGENESIS-ASSOCIATED PROTEIN 31A1-RELATED; 1.
DR Pfam; PF15371; DUF4599; 1.
DR Pfam; PF14650; FAM75; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006718};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 86..140
FT /note="SPATA31F3-like"
FT /evidence="ECO:0000259|Pfam:PF15371"
FT DOMAIN 352..710
FT /note="SPATA31"
FT /evidence="ECO:0000259|Pfam:PF14650"
FT REGION 45..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 583..614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 632..671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 858..916
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 929..949
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1036..1117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1270..1291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..75
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..125
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..173
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 337..356
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 583..612
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 653..671
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 880..906
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1067..1083
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1302 AA; 143182 MW; CAF6D17E5F47F530 CRC64;
MPRSQLLESN ASTPWVLDIF LTLVFALGFF FLLFPYFSYL RYDDPPSPSP GKRKCPVGRR
GRPRGRMKNH SLRGKALPGH TRVNLISLLG PHPDKGDFGQ LSGPDPPGEV GKRAPDGDSR
SSHETMEDAA PMLSPLASPD PRTKHPQDLA STPSPGPMTT SVSSLSASQA PEPSLPPETF
PAPPLRDSTL IIPSHCDSVA LPLGTVPQSL SLRKDLAASV PAISGLGGSN SQVSAFSWWQ
ETTRTWCVFN SSVQQDHLSR HPPETCQMEA GSPFLLNSDG QNVMGIQVIE RAKVNISEEK
ENDGSFPKQM SPEKHLNSLG NLVKSLDAEQ DPTTPKPFWN MGKNSKQLPS PQKLSDPRIL
QESFQKNYSQ LFWGLPSLHS ESLVANAWVT ERSYTLQSPP FLFNGISNVC PIQRETTMSP
LLFQAQPLSH LGPESQPFIS STPQFRPIPM AQAEAQAHLQ SSFPVLSPAF PSPIDNSGVA
CPASQIKVQV LCLPETQHPE WPLLRKQLEG GLALPPRVQK SQDVFSVSTP NLPQESLTSI
LPENFPISPE LRRQLEQHIQ KWFIQHQGNL GRIQESLDLM QLRDESSGTS QAKGKPRPWQ
SSTSTGESSK EAQKVKFQLE RDPCPHLGQI LGQTPQNLSR GMESFPGKVL GATSEESERD
LRKPLRSDSG SDLLRRTERN RIENVLKAHV GRKLGQINEG LIPVSVRRSW LAVNQAFPVS
NTHVKTSNLA PPKSGKACVN TAQVLPFLEP CTQQVLGAHI GRLWAKHRWG LPLRVLKPIQ
CFKLEKVSSL SLTQLAGPSS ATCEPGAGSK VEVATFLREP PMASLRQQVL TKASDMPDSL
LASSAACKQF QRAPLGIPSW NDHGPLKAPP AAQEGRWPSK PLTYSLTGST QQSRSLGAQS
SRAGETREAE PQPRVPLGTR MLANLQATGD DVRGFGAPGT SRSSLLPKMS VSQDPRQLCL
MEEVISEFEP GMATKSETQP QVCAAVVLLP DGQASVLPLV TENLAPQVPQ GHLQSMPAGN
MRASQELRDL MAARRSNLGH REPKNPNCQV SCKRQSPMFP PLHKSENSRK PNLEKHEERL
EGLRTPQPSP VRKTEDTRQD EGVQPLPSKK QPPSISHFGE NIKQFFQRVF SKKKSKPAPV
TAESQKTGKN RSCVYSSSAE AQGLMTAVGQ MLEEKMSLCH ARHASKVNQH KQEFQAPVCG
FPCNHRHPFY SEHSRMLSYA ASSQQATLKS QSCPNRERQI RDQQPLKSVR CNNEQWGLRH
PQLLLPKKAV SPVSPPQHWP KTPGASSHHH HCPRHCLLRG GI
//
