ID A0A1D5QNI6_MACMU Unreviewed; 689 AA.
AC A0A1D5QNI6;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Mitotic arrest deficient 1 like 1 {ECO:0000313|Ensembl:ENSMMUP00000049612.2};
GN Name=MAD1L1 {ECO:0000313|Ensembl:ENSMMUP00000049612.2,
GN ECO:0000313|VGNC:VGNC:74471};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000049612.2, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000049612.2}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000049612.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MAD1 family.
CC {ECO:0000256|ARBA:ARBA00008029}.
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DR AlphaFoldDB; A0A1D5QNI6; -.
DR SMR; A0A1D5QNI6; -.
DR Ensembl; ENSMMUT00000068581.2; ENSMMUP00000049612.2; ENSMMUG00000011659.4.
DR VEuPathDB; HostDB:ENSMMUG00000011659; -.
DR VGNC; VGNC:74471; MAD1L1.
DR GeneTree; ENSGT00390000001316; -.
DR Proteomes; UP000006718; Chromosome 3.
DR Bgee; ENSMMUG00000011659; Expressed in fibroblast and 21 other cell types or tissues.
DR ExpressionAtlas; A0A1D5QNI6; baseline.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 3.30.457.60; -; 1.
DR Gene3D; 6.10.250.90; -; 1.
DR InterPro; IPR008672; Mad1.
DR PANTHER; PTHR23168:SF0; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1; 1.
DR PANTHER; PTHR23168; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1; 1.
DR Pfam; PF05557; MAD; 2.
DR SUPFAM; SSF75704; Mitotic arrest deficient-like 1, Mad1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000006718}.
FT COILED 93..371
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 420..599
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 689 AA; 79906 MW; 6F2F3FCC7BDC24C0 CRC64;
MEDLGENTTV LSTLRSLNNF ISQRVEGGSG LDISTSAPGS LQMQYQQSMQ LEERAEQIRS
KSHLIQVERE KMQMELSHKR ARVELERAAS TSARNYEREV DRNQELLTRI RQLQEREAGA
EEKMQEQLER NRQCQQNLDA ASKRLREKED SLAQAGETIS ALKGRISELQ WSVMDQEMRV
KRLESEKQEL QEQLDLQHKK WQEANQKIQE LQASQEARAD HEQQIKDLEQ KLSLQEQDAA
IVKNMKSELV RLPRLERELK QLREESMHLR EMRETNGLLQ EELEGLQRKL GRQEKMQETL
VGLELENERL LAKLQSWERL DQTTGLSISA RGLEKARQQL QEELRQVSGQ LLEERKKRET
HEALARRLQK RVLLLTKERD GMRAILGSYD SELTSAEYSP QLTRRMREAE DMVQKVHSHS
AEMEAQLSQA LEELGGQKQR ADMLEMELKM LKSQSSSAEQ SFLFSREEVD TLRLKVEELE
GERRRLEEEK RMLEAQLERR VLQGDYDQSR TKVLHMSLNP ASVARQRLRE DHSQLQAECE
RLRGLLRAME RGGTVPTDLE AAAASLPSSK EVAELKKQVE SAELKNQRLK EVFQTKIQEF
RKACYTLTGY QIDITTENQY RLTSLYAEHP GDCLIFKATS PSGSKMQLLE TEFSHTVGEL
IEVHLRHQDS IPAFLSSLTL ELFSRQTVA
//
